No renderable structure data available
CC1=CC=C(C=C1)CCBrChemical Intermediate
Structures, identifiers and computed properties have been matched to the database record by CAS.
| Intermediates | 1-(2-bromoethyl)-4-methylbenzene |
|---|---|
| IUPAC Name | — |
| CAS Number | 6529-51-7 |
| Database ID | 570680 |
| Molecular Formula | — |
| Molecular Weight | — |
Product Information
1-(2-bromoethyl)-4-methylbenzene (CAS 6529-51-7) product identity, structure identifiers and related reaction data for chemical intermediate research and sourcing review.
Potential Applications
For professional research and industrial use only
Database ID 570680
Safety Notice
For professional research and industrial use only. Review the supplier safety data sheet before handling.
Synthesis data
12 reactions · 12 references
Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-6cac125095e048a38d96ca84bb7c2391Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-e76b976082fa4b84acb25a61fc34bae2Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-5cbb5a8e00b846e59125db42d9ab93a5Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-6cac125095e048a38d96ca84bb7c2391Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-6cac125095e048a38d96ca84bb7c2391Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: 1.0 g (9.35 mmol) of 4-ethylpyridine and 1.86 g (9.35 mmol) of 4-methylphenethyl bromide were reacted in the same manner as in Example 1. The reaction product was purified to obtain 2.07 g of the desired compound (yield: 98.4%). The resulting compound was identified as 1-(4-methylphenyl)-3-(4-pyridyl)-butane (hereinafter referred to as compound 7) by the following analytical results. The reaction product was purified
Source ID: ord-b94f3e175a914bafa6eb4e78d47d9684Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: 1.0 g (9.35 mmol) of 4-ethylpyridine and 1.86 g (9.35 mmol) of 4-methylphenethyl bromide were reacted in the same manner as in Example 1. The reaction product was purified to obtain 2.07 g of the desired compound (yield: 98.4%). The resulting compound was identified as 1-(4-methylphenyl)-3-(4-pyridyl)-butane (hereinafter referred to as compound 7) by the following analytical results. The reaction product was purified
Source ID: ord-b94f3e175a914bafa6eb4e78d47d9684Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: 2-(4-Methylphenyl)ethyl bromide (X: X=Br) (10 g, 0.05 mole) and sodium 4-nitrophenolate (XI) (8.1 g, 0.05 mole) were added to dimethylformamide (60 ml), and the mixture was reacted at 90° C. for 5 hours. Thereafter, the reaction mixture was treated in the same manner as in Example 12 to obtain 9.5 g of 4-[2-(4-methylphenyl)ethoxy]-nitrobenzene (VI) as white crystals (yield, 73.9%). the mixture was reacted at 90° C. for 5 hours Thereafter, the reaction mixture was treated in the same manner as in Example 12 to obtain
Source ID: ord-e62dd0aa8a7f41d4a22d917b5c66675cConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: 2-(4-Methylphenyl)ethyl bromide (X: X=Br) (10 g, 0.05 mole) and sodium 4-nitrophenolate (XI) (8.1 g, 0.05 mole) were added to dimethylformamide (60 ml), and the mixture was reacted at 90° C. for 5 hours. Thereafter, the reaction mixture was treated in the same manner as in Example 12 to obtain 9.5 g of 4-[2-(4-methylphenyl)ethoxy]-nitrobenzene (VI) as white crystals (yield, 73.9%). the mixture was reacted at 90° C. for 5 hours Thereafter, the reaction mixture was treated in the same manner as in Example 12 to obtain
Source ID: ord-e62dd0aa8a7f41d4a22d917b5c66675cConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: (E)-3-{4-Oxo-spiro[chromane-2,4′-piperidine]-6-yl}-acrylic acid methyl ester (253 mg, 0.749 mmol, Intermediate 1, hydrochloride salt) was alkylated using 1-(2-bromo-ethyl)-4-methyl-benzene (0.23 ml, 1.5 mmol) as described in Example 56, Step A, giving (E)-3-{1′-[2-(4-methyl-phenyl)-ethyl]-4-oxo-spiro[chromane-2,4′-piperidine]-6-yl}-acrylic acid methyl ester (282 mg) as a light brown solid.
Source ID: ord-44d7254a0ad64197b7c57c9311faf29fConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: 2-(4-Methylphenyl)ethyl bromide (X: X=Br) (10 g, 0.05 mole) and sodium 4-nitrophenolate (XI) (8.1 g, 0.05 mole) were added to dimethylformamide (60 ml), and the mixture was reacted at 90° C. for 5 hours. Thereafter, the reaction mixture was treated in the same manner as in Example 12 to obtain 9.5 g of 4-[2-(4-methylphenyl)ethoxy]nitrobenzene (VI) as white crystals (yield, 73.9%). the mixture was reacted at 90° C. for 5 hours Thereafter, the reaction mixture was treated in the same manner as in Example 12 to obtain
Source ID: ord-600c5b91b211400d851f7be8f6e0f06eConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: 2-(4-Methylphenyl)ethyl bromide (X: X=Br) (10 g, 0.05 mole) and sodium 4-nitrophenolate (XI) (8.1 g, 0.05 mole) were added to dimethylformamide (60 ml), and the mixture was reacted at 90° C. for 5 hours. Thereafter, the reaction mixture was treated in the same manner as in Example 12 to obtain 9.5 g of 4-[2-(4-methylphenyl)ethoxy]nitrobenzene (VI) as white crystals (yield, 73.9%). the mixture was reacted at 90° C. for 5 hours Thereafter, the reaction mixture was treated in the same manner as in Example 12 to obtain
Source ID: ord-600c5b91b211400d851f7be8f6e0f06ePubChem References
These sources are listed in the compound's public database record.
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