1,2-dibromoethylbenzene

Conditions: temp:40.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: To a stirred suspension of 18.6 g of the disodium salt of 1,2-dicyano-1,2-dimercaptoethylene under nitrogen is added 26.4 g of 1,2-dibromo-1-phenylethane. After stirring at 40° C. for one-half hour, the mixture is heated under reflux for 1.5 hours, cooled, filtered, and the solvent removed under reduced pressure. The residue is crystallized by filtration with carbon tetrachloride to give the product, 2,3-dicyano-5,6-dihydro-5-phenyl-p-dithiin, as golden brown crystals, melting point 121.5° C. to 124° C. A purified sample had melting point 125° C. to 126.5° C. the mixture is heated under reflux for 1.5 hours cooled filtered the solvent removed under reduced pressure The residue is crystallized by filtration with carbon tetrachloride

Conditions: temp:40.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: To a stirred suspension of 18.6 g of the disodium salt of 1,2-dicyano-1,2-dimercaptoethylene under nitrogen is added 26.4 g of 1,2-dibromo-1-phenylethane. After stirring at 40° C. for one-half hour, the mixture is heated under reflux for 1.5 hours, cooled, filtered, and the solvent removed under reduced pressure. The residue is crystallized by filtration with carbon tetrachloride to give the product, 2,3-dicyano-5,6-dihydro-5-phenyl-p-dithiin, as golden brown crystals, melting point 121.5° C. to 124° C. A purified sample had melting point 125° C. to 126.5° C. the mixture is heated under reflux for 1.5 hours cooled filtered the solvent removed under reduced pressure The residue is crystallized by filtration with carbon tetrachloride

Conditions: temp:40.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: To a stirred suspension of 18.6 g of the disodium salt of 1,2-dicyano-1,2-dimercaptoethylene under nitrogen is added 26.4 g of 1,2-dibromo-1-phenylethane. After stirring at 40° C. for one-half hour, the mixture is heated under reflux for 1.5 hours, cooled, filtered, and the solvent removed under reduced pressure. The residue is crystallized by filtration with carbon tetrachloride to give the product, 2,3-dicyano-5,6-dihydro-5-phenyl-p-dithiin, as golden brown crystals, melting point 121.5° C. to 124° C. A purified sample had melting point 125° C. to 126.5° C. the mixture is heated under reflux for 1.5 hours cooled filtered the solvent removed under reduced pressure The residue is crystallized by filtration with carbon tetrachloride

Conditions: temp:100.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: (1,2-Dibromoethyl)benzene (21 g) was treated with 2-mercaptobenzimidazole (17 g) in dimethylformamide (100 ml) and the mixture was heated at 100° C. for 36 hours. On cooling, the solid material was removed by filtration and recrystallised from methanol and ethyl acetate to give the title compound as the hydrobromide salt (13.68 g). mp 207°-210° C. On cooling the solid material was removed by filtration recrystallised from methanol and ethyl acetate

Conditions: temp:100.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: (1,2-Dibromoethyl)benzene (21 g) was treated with 2-mercaptobenzimidazole (17 g) in dimethylformamide (100 ml) and the mixture was heated at 100° C. for 36 hours. On cooling, the solid material was removed by filtration and recrystallised from methanol and ethyl acetate to give the title compound as the hydrobromide salt (13.68 g). mp 207°-210° C. On cooling the solid material was removed by filtration recrystallised from methanol and ethyl acetate

Conditions: temp:45.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: A mixture of 14.2 g (0.1 mole) of 2-mercapto-4,6-diamino-pyrimidine, 30.4 g (0.115 mole) of (1,2-dibromo-ethyl)-benzene, 200 ml of dimethyl formamide and 13.8 g (0.1 mole) of potassium carbonate is stirred at 45° C. for 6 hours. The reaction mixture is cooled, the precipitate is filtered, washed with water and dried. Thus 26.0 g of the desired compound are obtained, yield 80%, m.p.: above 300° C. The reaction mixture is cooled the precipitate is filtered washed with water dried

Conditions: temp:40.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: To a stirred suspension of 18.6 g of the disodium salt of 1,2-dicyano-1,2-dimercaptoethylene under nitrogen is added 26.4 g of 1,2-dibromo-1-phenylethane. After stirring at 40° C. for one-half hour, the mixture is heated under reflux for 1.5 hours, cooled, filtered, and the solvent removed under reduced pressure. The residue is crystallized by filtration with carbon tetrachloride to give the product, 2,3-dicyano-5,6-dihydro-5-phenyl-p-dithiin, as golden brown crystals, melting point 121.5° C. to 124° C. A purified sample had melting point 125° C. to 126.5° C. the mixture is heated under reflux for 1.5 hours cooled filtered the solvent removed under reduced pressure The residue is crystallized by filtration with carbon tetrachloride