4-bromofuran-2-carboxamide

Conditions: temp:95.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: A mixture of 4-bromofuran-2-carboxamide 124 (0.85 g, 4.47 mmol) and chloral (0.78 mL) in xylene was heated at 95° C. for 1.5 hours. The mixture was concentrated to give 4-bromo-N-(2,2,2-trichloro-1-hydroxyethyl)furan-2-carboxamide 125 as a tan solid that was used without further purification. The mixture was concentrated