2,4,6-trimethylbenzoyl chloride

Conditions: temp:0.00; pressure:0.00; stir:

Conditions: temp:0.00; pressure:0.00; stir:

Conditions: temp:0.00; pressure:0.00; stir:

Conditions: temp:0.00; pressure:0.00; stir:

Conditions: temp:0.00; pressure:0.00; stir:

Conditions: temp:0.00; pressure:0.00; stir:

Conditions: temp:0.00; pressure:0.00; stir:

Conditions: temp:0.00; pressure:0.00; stir:

Conditions: temp:0.00; pressure:0.00; stir:

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: The compound of example 153 was prepared analogous to compound of example 97 by reaction of compound of example 6 with 2,4,6-trimethyl benzoyl chloride.

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: A solution of 16.2 g of diisopropylamine in 50 ml of tetrahydrofuran (THF) is cooled to -10° C. 100 ml of butyllithium in hexane (1.6 M) are added dropwise. Then, at -40° C., first 9.0 g of 4-methylphenylphosphine and, subsequently, a solution of 29.22 g of 2,4,6-trimethylbenzoyl chloride in 150 ml of THF are added. The solution is stirred for 1.5 hours and then the solvent is removed under reduced pressure, to give 28.0 g of bis(2,4,6-trimethylbenzoyl)-4-methylphenylphosphine as a yellow powder. the solvent is removed under reduced pressure

Conditions: temp:0.00; pressure:0.00; stir: