2-chloro-2-methylpropanal

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: To a mixture of 45 g (0.424 mol) of 2-chloro-2-methylpropanal, 99.6 ml (1.69 mol) of ethanol, 81.6 g (0.55 mol) of triethylorthoformate in 100 ml of methylene chloride was added 800 mg (4.2 mmol) of p-toluenesulfonic acid and the mixture was stirred at room temperature. After adding 2 g of potassium carbonate to the above mixture, the reaction mixture was stirred (2 min.), and filtered. The filtrate was concentrated (80° C.) to remove methylene chloride and the residue was distilled (2×) to afford 52 g (68.2%) of 2-chloro-2-methylpropanal diethyl acetal, b.p. 55°-65° C./25 mm. the reaction mixture was stirred (2 min.) filtered The filtrate was concentrated (80° C.) to remove methylene chloride the residue was distilled (2×)