(5-bromo-2,3-difluorophenyl)methanol

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: tert-butyl 4-(3,4-difluoro-5-(hydroxymethyl)phenyl)-3-oxopiperazine-1-carboxylate was prepared following the procedure in Example 27 (Step ii) using (5-bromo-2,3-difluorophenyl)methanol and tert-butyl 3-oxopiperazine-1-carboxylate.

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: tert-butyl 4-(3,4-difluoro-5-(hydroxymethyl)phenyl)-3-oxopiperazine-1-carboxylate was prepared following the procedure in Example 27 (Step ii) using (5-bromo-2,3-difluorophenyl)methanol and tert-butyl 3-oxopiperazine-1-carboxylate.

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: tert-butyl 4-(3,4-difluoro-5-(hydroxymethyl)phenyl)-3-oxopiperazine-1-carboxylate was prepared following the procedure in Example 27 (Step ii) using (5-bromo-2,3-difluorophenyl)methanol and tert-butyl 3-oxopiperazine-1-carboxylate.