2-chloro-1-isocyanato-3-methylbenzene

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: 6,7-Dimethoxy-4-(4-aminophenoxy)quinoline (52 mg) was dissolved in toluene (5 ml) with heat, 2-chloro-3-methylphenyl isocyanate (0.2 ml) was added, and the admixture was refluxed with heat for 12 minutes. The reaction solution was purified by column chromatography on silica gel eluting with chloroform/acetone (10/1) to obtain 30 mg of the title compound (yield: 37%). with heat the admixture was refluxed with heat for 12 minutes The reaction solution was purified by column chromatography on silica gel eluting with chloroform/acetone (10/1)