1,3-bis(3-methylbutyl)urea

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: Heated was a mixture of urea 0.601 g (10.0 mmol) and 3-methylbutylamine 5.0 mL (ca. 6 equivalents) at 150° C. for 24 hours attaching with a reflux cooler and during which time added more 3-methylbutylamine 2.5 mL. Removed was the excess amine under the reduced pressure and allowed to cool to room temperature to give a colorless solid. Purification by recrystallization from ethyl ether gave N,N′-bis(3-methylbutyl)urea 1.29 g as white plates (64.5% yield). Heated Removed to give a colorless solid Purification by recrystallization from ethyl ether