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CNCCNC1=CC=CC=C1Chemical Intermediate
Structures, identifiers and computed properties have been matched to the database record by CAS.
| Intermediates | N-methyl-N'-phenylethane-1,2-diamine |
|---|---|
| IUPAC Name | — |
| CAS Number | 64469-32-5 |
| Database ID | 10582940 |
| Molecular Formula | — |
| Molecular Weight | — |
Product Information
N-methyl-N'-phenylethane-1,2-diamine (CAS 64469-32-5) product identity, structure identifiers and related reaction data for chemical intermediate research and sourcing review.
Potential Applications
For professional research and industrial use only
Database ID 10582940
Safety Notice
For professional research and industrial use only. Review the supplier safety data sheet before handling.
Synthesis data
12 reactions · 12 references
Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-a7851bb2b1a248c5b7662315796f281cConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: Here, 3-(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl)-1-chloropropane (9 g, 0.0336 mol) is heated to 130° C. for 30 minutes with N-(2-phenylaminoethyl)-methylamine (11 g, 0.073 mol). After cooling, the reaction mixture is distributed between water and diethylether. The organic phase is separated, dried over sodium sulfate and concentrated by evaporation. The residue is recrystallized from toluene/petroleum ether. After cooling The organic phase is separated dried over sodium sulfate concentrated by evaporation The residue is recrystallized from toluene/petroleum ether
Source ID: ord-cec3cf093d2642b99435172808ba3265Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-a7851bb2b1a248c5b7662315796f281cConditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-a7851bb2b1a248c5b7662315796f281cConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: In a manner similar to preparation 1, react N-methyl-N'-phenyl-1,2-ethanediamine with 2,3-dibromopropanamide to obtainthe title compound. In a manner similar to preparation 1
Source ID: ord-5d87b3ec1677429797f935ed4b63be97Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: In a manner similar to preparation 1, react N-methyl-N'-phenyl-1,2-ethanediamine with 2,3-dibromopropanamide to obtainthe title compound. In a manner similar to preparation 1
Source ID: ord-5d87b3ec1677429797f935ed4b63be97Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: Here, 3-(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl)-1-chloropropane (9 g, 0.0336 mol) is heated to 130° C. for 30 minutes with N-(2-phenylaminoethyl)-methylamine (11 g, 0.073 mol). After cooling, the reaction mixture is distributed between water and diethylether. The organic phase is separated, dried over sodium sulfate and concentrated by evaporation. The residue is recrystallized from toluene/petroleum ether. After cooling The organic phase is separated dried over sodium sulfate concentrated by evaporation The residue is recrystallized from toluene/petroleum ether
Source ID: ord-cec3cf093d2642b99435172808ba3265Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: Here, 3-(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl)-1-chloropropane (9 g, 0.0336 mol) is heated to 130° C. for 30 minutes with N-(2-phenylaminoethyl)-methylamine (11 g, 0.073 mol). After cooling, the reaction mixture is distributed between water and diethylether. The organic phase is separated, dried over sodium sulfate and concentrated by evaporation. The residue is recrystallized from toluene/petroleum ether. After cooling The organic phase is separated dried over sodium sulfate concentrated by evaporation The residue is recrystallized from toluene/petroleum ether
Source ID: ord-cec3cf093d2642b99435172808ba3265Conditions: temp:170.01; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A mixture of aniline hydrochloride (13.0 g, 0.10 mole), 3-methyl-2-oxazolidinone (11.0 g, 0.109 mole) and 35 ml of 2-(2-methoxyethoxy)ethanol was heated to 170° C. in an oil bath. The reaction mixture became homogenous and carbon dioxide evolution occurred on heating. After 17 hours, the reaction was allowed to cool to room temperature. After a workup procedure similar to that described in Example 1 and distillation at 105° C. to 110° C. (0.4 mm), an 81 percent distilled yield of the product was obtained as a clear liquid. Product confirmation was made by the use of spectra evidence. on heating to cool to room temperature After a workup procedure similar to that described in Example 1 and distillation at 105° C. to 110° C. (0.4 mm) an 81 percent distilled yield of the product was obtained as a clear liquid
Source ID: ord-b4402926e87e4dc68f87a8052c946b9dConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: In a manner similar to preparation 1, react N-methyl-N'-phenyl-1,2-ethanediamine with 2,3-dibromopropanamide to obtain the title compound. In a manner similar to preparation 1
Source ID: ord-ddaa1cbd19ad4e20bc24811ab1615479Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: In a manner similar to preparation 1, react N-methyl-N'-phenyl-1,2-ethanediamine with 2,3-dibromopropanamide to obtainthe title compound. In a manner similar to preparation 1
Source ID: ord-5d87b3ec1677429797f935ed4b63be97Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: Here, 3-(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-on-3-yl)-1-chloropropane (9 g, 0.0336 mol) is heated to 130° C. for 30 minutes with N-(2-phenylaminoethyl)-methylamine (11 g, 0.073 mol). After cooling, the reaction mixture is distributed between water and diethylether. The organic phase is separated, dried over sodium sulfate and concentrated by evaporation. The residue is recrystallized from toluene/petroleum ether. After cooling The organic phase is separated dried over sodium sulfate concentrated by evaporation The residue is recrystallized from toluene/petroleum ether
Source ID: ord-cec3cf093d2642b99435172808ba3265PubChem References
These sources are listed in the compound's public database record.
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