4-Bromobenzyloxirane

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: A mixture of 90 parts of 2-(4-bromophenylmethyl)oxirane, 8 parts of ethanedioic acid, 100 parts of water and 300 parts of 1,4-dioxane is stirred and refluxed overnight. The reaction mixture is evaporated. The residue is dissolved in trichloromethane. The solution is washed with 110 parts of a sodium hydroxide solution 10%, dried, filtered and evaporated. This The is distilled (bp. 165° C at 0.6 mm. pressure). The distillate is crystallized from 2,2'-oxybispropane. The product is filtered off and dried, yielding 25 parts of 3-(4-bromophenyl)-1,2-propanediol; mp. 60.6° C. refluxed overnight The reaction mixture is evaporated The residue is dissolved in trichloromethane The solution is washed with 110 parts of a sodium hydroxide solution 10% dried filtered evaporated This The is distilled (bp. 165° C at 0.6 mm. pressure) The distillate is crystallized from 2,2'-oxybispropane The product is filtered off dried

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: A mixture of 90 parts of 2-(4-bromophenylmethyl)oxirane, 8 parts of ethanedioic acid, 100 parts of water and 300 parts of 1,4-dioxane is stirred and refluxed overnight. The reaction mixture is evaporated. The residue is dissolved in trichloromethane. The solution is washed with 110 parts of a sodium hydroxide solution 10%, dried, filtered and evaporated. This The is distilled (bp. 165° C at 0.6 mm. pressure). The distillate is crystallized from 2,2'-oxybispropane. The product is filtered off and dried, yielding 25 parts of 3-(4-bromophenyl)-1,2-propanediol; mp. 60.6° C. refluxed overnight The reaction mixture is evaporated The residue is dissolved in trichloromethane The solution is washed with 110 parts of a sodium hydroxide solution 10% dried filtered evaporated This The is distilled (bp. 165° C at 0.6 mm. pressure) The distillate is crystallized from 2,2'-oxybispropane The product is filtered off dried

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: A mixture of 90 parts of 2-(4-bromophenylmethyl)oxirane, 8 parts of ethanedoic acid, 100 parts of water and 300 parts of 1,4-dioxane is stirred and refluxed overnight. The reaction mixture is evaporated. The residue is dissolved in trichloromethane. The solution is washed with 110 parts of a sodium hydroxide solution 10%, dried, filtered and evaporated. The residue is distilled (bp. 165° C. at 0.6 mm. pressure). The distillate is crystallized from 2,2'-oxybispropane. The product is filtered off and dried, yielding 25 parts of 3-(4-bromophenyl)-1,2-propanediol; mp. 60.6° C. refluxed overnight The reaction mixture is evaporated The residue is dissolved in trichloromethane The solution is washed with 110 parts of a sodium hydroxide solution 10% dried filtered evaporated The residue is distilled (bp. 165° C. at 0.6 mm. pressure) The distillate is crystallized from 2,2'-oxybispropane The product is filtered off dried

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: A mixture of 90 parts of 2-(4-bromophenylmethyl)oxirane, 8 parts of ethanedioic acid, 100 parts of water and 300 parts of 1,4-dioxane is stirred and refluxed overnight. The reaction mixture is evaporated. The residue is dissolved in trichloromethane. The solution is washed with 110 parts of a sodium hydroxide solution 10%, dried, filtered and evaporated. The residue is distilled (bp. 165° C. at 0.6 mm. pressure). The distillate is crystallized from 2,2'-oxybispropane. The product is filtered off and dried, yielding 25 parts of 3-(4-bromophenyl)-1,2-propanediol; mp. 60.6° C. refluxed overnight The reaction mixture is evaporated The residue is dissolved in trichloromethane The solution is washed with 110 parts of a sodium hydroxide solution 10% dried filtered evaporated The residue is distilled (bp. 165° C. at 0.6 mm. pressure) The distillate is crystallized from 2,2'-oxybispropane The product is filtered off dried

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: A mixture of 90 parts of 2-(4-bromophenylmethyl)oxirane, 8 parts of ethanedioic acid, 100 parts of water and 300 parts of 1,4-dioxane is stirred and refluxed overnight. The reaction mixture is evaporated. The residue is dissolved in trichloromethane. The solution is washed with 110 parts of a sodium hydroxide solution 10%, dried, filtered and evaporated. This The is distilled (bp. 165° C at 0.6 mm. pressure). The distillate is crystallized from 2,2'-oxybispropane. The product is filtered off and dried, yielding 25 parts of 3-(4-bromophenyl)-1,2-propanediol; mp. 60.6° C. refluxed overnight The reaction mixture is evaporated The residue is dissolved in trichloromethane The solution is washed with 110 parts of a sodium hydroxide solution 10% dried filtered evaporated This The is distilled (bp. 165° C at 0.6 mm. pressure) The distillate is crystallized from 2,2'-oxybispropane The product is filtered off dried