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COC(=O)C(=O)CCCBrChemical Intermediate
Structures, identifiers and computed properties have been matched to the database record by CAS.
| Intermediates | methyl 5-bromo-2-oxopentanoate |
|---|---|
| IUPAC Name | — |
| CAS Number | 62691-70-7 |
| Database ID | 13769949 |
| Molecular Formula | — |
| Molecular Weight | — |
Product Information
methyl 5-bromo-2-oxopentanoate (CAS 62691-70-7) product identity, structure identifiers and related reaction data for chemical intermediate research and sourcing review.
Potential Applications
For professional research and industrial use only
Database ID 13769949
Safety Notice
For professional research and industrial use only. Review the supplier safety data sheet before handling.
Synthesis data
12 reactions · 12 references
Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-8a02dec33d3f43b9a9f2cc68eb41ea43Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: Jones' reagent (CrO3 : 9.58 g, H2SO4 : 8.47 ml, H2O: 36.8 ml) was added to a magnetically stirred solution of Part (3) compound (12.53 g, 59.3 mmole) in acetone (150 ml) at room temperature. The addition was controlled to maintain the temperature below 35° C. After the completion of the addition, the reaction was stirred at room temperature for 45 minutes. Isopropyl alcohol (30 ml) was added dropwise and stirred for 30 minutes. The reaction was then diluted with H2O (500 ml) and the products were extracted with CH2Cl2 (1 l.). The CH2Cl2 layer was washed with brine (100 ml×3) and dried over MgSO4. Filtration and evaporation of solvents gave the title compound (11.4 g, 54.5 mmole, 92%) as a colorless liquid. The addition to maintain the temperature below 35° C After the completion of the addition stirred for 30 minutes the products were extracted with CH2Cl2 (1 l.) The CH2Cl2 layer was washed with brine (100 ml×3) dried over MgSO4 Filtration and evaporation of solvents
Source ID: ord-045c287926a84d539f6990e143d71b15Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: Jones' reagent (CrO3 : 9.58 g, H2SO4 : 8.47 ml, H2O: 36.8 ml) was added to a magnetically stirred solution of Part (3) compound (12.53 g, 59.3 mmole) in acetone (150 ml) at room temperature. The addition was controlled to maintain the temperature below 35° C. After the completion of the addition, the reaction was stirred at room temperature for 45 minutes. Isopropyl alcohol (30 ml) was added dropwise and stirred for 30 minutes. The reaction was then diluted with H2O (500 ml) and the products were extracted with CH2Cl2 (1 l.). The CH2Cl2 layer was washed with brine (100 ml×3) and dried over MgSO4. Filtration and evaporation of solvents gave the title compound (11.4 g, 54.5 mmole, 92%) as a colorless liquid. The addition to maintain the temperature below 35° C After the completion of the addition stirred for 30 minutes the products were extracted with CH2Cl2 (1 l.) The CH2Cl2 layer was washed with brine (100 ml×3) dried over MgSO4 Filtration and evaporation of solvents
Source ID: ord-5a81624196e64e628ce2e61118238cc2Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: Jones' reagent (CrO3 :9.58 g, H2SO4 : 8.47 ml, H2O:36.8 ml) was added to a magnetically stirred solution of Part (3) compound (12.53 g, 59.3 mmole) in acetone (150 ml) at room temperature. The addition was controlled to maintain the temperature below 35° C. After the completion of the addition, the reaction was stirred at room temperature for 45 minutes. Isopropyl alcohol (30 ml) was added dropwise and stirred for 30 minutes. The reaction was then diluted with H2O (500 ml) and the products were extracted with CH2Cl2 (1 1.). The CH2Cl2 layer was washed with brine (100 ml×3) and dried over MgSO4. Filtration and evaporation of solvents gave the title compound (11.4 g, 54.5 mmole, 92%) as a colorless liquid. The addition to maintain the temperature below 35° C After the completion of the addition stirred for 30 minutes the products were extracted with CH2Cl2 (1 1.) The CH2Cl2 layer was washed with brine (100 ml×3) dried over MgSO4 Filtration and evaporation of solvents
Source ID: ord-29b02da7d9d74038a3f2288b5b06aa7aConditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-8a02dec33d3f43b9a9f2cc68eb41ea43Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: Jones' reagent (CrO3 : 9.58 g, H2SO4 : 8.47 ml, H2O: 36.8 ml) was added to a magnetically stirred solution of Part (3) compound (12.53 g, 59.3 mmole) in acetone (150 ml) at room temperature. The addition was controlled to maintain the temperature below 35° C. After the completion of the addition, the reaction was stirred at room temperature for 45 minutes. Isopropyl alcohol (30 ml) was added dropwise and stirred for 30 minutes. The reaction was then diluted with H2O (500 ml) and the products were extracted with CH2Cl2 (1 l.). The CH2Cl2 layer was washed with brine (100 ml×3) and dried over MgSO4. Filtration and evaporation of solvents gave the title compound (11.4 g, 54.5 mmole, 92%) as a colorless liquid. The addition to maintain the temperature below 35° C After the completion of the addition stirred for 30 minutes the products were extracted with CH2Cl2 (1 l.) The CH2Cl2 layer was washed with brine (100 ml×3) dried over MgSO4 Filtration and evaporation of solvents
Source ID: ord-0fe54f7a1863492fab214951ac63ec3fConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: Jones' reagent (CrO3 : 9.58 g, H2SO4 : 8.47 ml, H2O: 36.8 ml) was added to a magnetically stirred solution of Part (3) compound (12.53 g, 59.3 mmole) in acetone (150 ml) at room temperature. The addition was controlled to maintain the temperature below 35° C. After the completion of the addition, the reaction was stirred at room temperature for 45 minutes. Isopropyl alcohol (30 ml) was added dropwise and stirred for 30 minutes. The reaction was then diluted with H2O (500 ml) and the products were extracted with CH2Cl2 (1 l.). The CH2Cl2 layer was washed with brine (100 ml×3) and dried over MgSO4. Filtration and evaporation of solvents gave the title compound (11.4 g, 54.5 mmole, 92%) as a colorless liquid. The addition to maintain the temperature below 35° C After the completion of the addition stirred for 30 minutes the products were extracted with CH2Cl2 (1 l.) The CH2Cl2 layer was washed with brine (100 ml×3) dried over MgSO4 Filtration and evaporation of solvents
Source ID: ord-4e2cd350fe7c4d4b8bde57090990c9c2Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: Jones' reagent (CrO3 : 9.58 g, H2SO4 : 8.47 ml, H2O: 36.8 ml) was added to a magnetically stirred solution of Part (3) compound (12.53 g, 59.3 mmole) in acetone (150 ml) at room temperature. The addition was controlled to maintain the temperature below 35° C. After the completion of the addition, the reaction was stirred at room temperature for 45 minutes. Isopropyl alcohol (30 ml) was added dropwise and stirred for 30 minutes. The reaction was then diluted with H2O (500 ml) and the products were extracted with CH2Cl2 (1 l.). The CH2Cl2 layer was washed with brine (100 ml×3) and dried over MgSO4. Filtration and evaporation of solvents gave the title compound (11.4 g, 54.5 mmole, 92%) as a colorless liquid. The addition to maintain the temperature below 35° C After the completion of the addition stirred for 30 minutes the products were extracted with CH2Cl2 (1 l.) The CH2Cl2 layer was washed with brine (100 ml×3) dried over MgSO4 Filtration and evaporation of solvents
Source ID: ord-a6243fdd763d4e93800122d0d528c111Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: Jones' reagent (CrO3 : 9.58 g, H2SO4 : 8.47 ml, H2O: 36.8 ml) was added to a magnetically stirred solution of Part (3) compound (12.53 g, 59.3 mmole) in acetone (150 ml) at room temperature. The addition was controlled to maintain the temperature below 35° C. After the completion of the addition, the reaction was stirred at room temperature for 45 minutes. Isopropyl alcohol (30 ml) was added dropwise and stirred for 30 minutes. The reaction was then diluted with H2O (500 ml) and the products were extracted with CH2Cl2 (1 l.). The CH2Cl2 layer was washed with brine (100 ml×3) and dried over MgSO4. Filtration and evaporation of solvents gave the title compound (11.4 g, 54.5 mmole, 92%) as a colorless liquid. The addition to maintain the temperature below 35° C After the completion of the addition stirred for 30 minutes the products were extracted with CH2Cl2 (1 l.) The CH2Cl2 layer was washed with brine (100 ml×3) dried over MgSO4 Filtration and evaporation of solvents
Source ID: ord-79f2efaf88654c86982ed7192d7666f1Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: Jones' reagent (CrO3 : 9.58 g, H2SO4 : 8.47 ml, H2O: 36.8 ml) was added to a magnetically stirred solution of Part (3) compound (12.53 g, 59.3 mmole) in acetone (150 ml) at room temperature. The addition was controlled to maintain the temperature below 35° C. After the completion of the addition, the reaction was stirred at room temperature for 45 minutes. Isopropyl alcohol (30 ml) was added dropwise and stirred for 30 minutes. The reaction was then diluted with H2O (500 ml) and the products were extracted with CH2Cl2 (1 l.). The CH2Cl2 layer was washed with brine (100 ml×3) and dried over MgSO4. Filtration and evaporation of solvents gave the title compound (11.4 g, 54.5 mmole, 92%) as a colorless liquid. The addition to maintain the temperature below 35° C After the completion of the addition stirred for 30 minutes the products were extracted with CH2Cl2 (1 l.) The CH2Cl2 layer was washed with brine (100 ml×3) dried over MgSO4 Filtration and evaporation of solvents
Source ID: ord-045c287926a84d539f6990e143d71b15Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: Jones' reagent (CrO3 : 9.58 g, H2SO4 : 8.47 ml, H2O: 36.8 ml) was added to a magnetically stirred solution of Part (3) compound (12.53 g, 59.3 mmole) in acetone (150 ml) at room temperature. The addition was controlled to maintain the temperature below 35° C. After the completion of the addition, the reaction was stirred at room temperature for 45 minutes. Isopropyl alcohol (30 ml) was added dropwise and stirred for 30 minutes. The reaction was then diluted with H2O (500 ml) and the products were extracted with CH2Cl2 (1 l.). The CH2Cl2 layer was washed with brine (100 ml×3) and dried over MgSO4. Filtration and evaporation of solvents gave the title compound (11.4 g, 54.5 mmole, 92%) as a colorless liquid. The addition to maintain the temperature below 35° C After the completion of the addition stirred for 30 minutes the products were extracted with CH2Cl2 (1 l.) The CH2Cl2 layer was washed with brine (100 ml×3) dried over MgSO4 Filtration and evaporation of solvents
Source ID: ord-5a81624196e64e628ce2e61118238cc2Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: Jones' reagent (CrO3 :9.58 g, H2SO4 : 8.47 ml, H2O:36.8 ml) was added to a magnetically stirred solution of Part (3) compound (12.53 g, 59.3 mmole) in acetone (150 ml) at room temperature. The addition was controlled to maintain the temperature below 35° C. After the completion of the addition, the reaction was stirred at room temperature for 45 minutes. Isopropyl alcohol (30 ml) was added dropwise and stirred for 30 minutes. The reaction was then diluted with H2O (500 ml) and the products were extracted with CH2Cl2 (1 1.). The CH2Cl2 layer was washed with brine (100 ml×3) and dried over MgSO4. Filtration and evaporation of solvents gave the title compound (11.4 g, 54.5 mmole, 92%) as a colorless liquid. The addition to maintain the temperature below 35° C After the completion of the addition stirred for 30 minutes the products were extracted with CH2Cl2 (1 1.) The CH2Cl2 layer was washed with brine (100 ml×3) dried over MgSO4 Filtration and evaporation of solvents
Source ID: ord-29b02da7d9d74038a3f2288b5b06aa7aPubChem References
These sources are listed in the compound's public database record.
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