2-(benzylamino)ethanol;hydrochloride

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: The reactions of Examples 1 and 2 are repeated with equimolar quantities of N-hydroxyethylbenzylamine hydrochloride or N-chloroethylbenzylamine hydrochloride to give 1,2,3,4-tetrahydroisoquinoline. The use of N-chloroethyl-2,3-dichlorobenzylamine as the base gives good yields of 7,8-dichlorol,2,3,4-tetrahydroisoquinoline.