No renderable structure data available
C1=CC=C(C=C1)CNS(=O)(=O)ClChemical Intermediate
Structures, identifiers and computed properties have been matched to the database record by CAS.
| Intermediates | N-benzylsulfamoyl chloride |
|---|---|
| IUPAC Name | — |
| CAS Number | 56379-96-5 |
| Database ID | 13529095 |
| Molecular Formula | — |
| Molecular Weight | — |
Product Information
N-benzylsulfamoyl chloride (CAS 56379-96-5) product identity, structure identifiers and related reaction data for chemical intermediate research and sourcing review.
Potential Applications
For professional research and industrial use only
Database ID 13529095
Safety Notice
For professional research and industrial use only. Review the supplier safety data sheet before handling.
Synthesis data
12 reactions · 12 references
Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-84f8d95e3b304eb1a1adaec1f0a3904bConditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-84f8d95e3b304eb1a1adaec1f0a3904bConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A solution of benzylsulfamoyl chloride (168 g) in anhydrous THF (300 ml) is added dropwise to a stirred solution of N-carbomethoxy-O-methylisourea (107 g) and triethylamine (90 g) in anhydrous THF (800 ml) under nitrogen at -70° C. The resulting suspension is warmed to RT, filtered and the filtrate evaporated in vacuo. The residue is partitioned between methylene chloride and 0.5N aq. HCl. The organic layer is dried, filtered, and concentrated in vacuo affording the desired product as an oil. filtered the filtrate evaporated in vacuo The residue is partitioned between methylene chloride and 0.5N aq. HCl The organic layer is dried filtered concentrated in vacuo
Source ID: ord-4099f6da5a8147cea0efd2977b40bde9Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A solution of benzylsulfamoyl chloride (168 g) in anhydrous THF (300 ml) is added dropwise to a stirred solution of N-carbomethoxy-O-methylisourea (107 g) and triethylamine (90 g) in anhydrous THF (800 ml) under nitrogen at -70° C. The resulting suspension is warmed to RT, filtered and the filtrate evaporated in vacuo. The residue is partitioned between methylene chloride and 0.5N aq. HCl. The organic layer is dried, filtered, and concentrated in vacuo affording the desired product as an oil. filtered the filtrate evaporated in vacuo The residue is partitioned between methylene chloride and 0.5N aq. HCl The organic layer is dried filtered concentrated in vacuo
Source ID: ord-4099f6da5a8147cea0efd2977b40bde9Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A stirred mixture of benzylsulfamic acid (73 g), PCl5 (81 g) in toluene (540 ml) is heated to 40°-50° C. for one hour and refluxed for about 3 hours. The cooled mixture is filtered through Celite and the filtrate concentrated in vacuo to remove the toluene affording the desired product as a liquid. is heated to 40°-50° C. for one hour refluxed for about 3 hours The cooled mixture is filtered through Celite the filtrate concentrated in vacuo to remove the toluene affording the desired product as a liquid
Source ID: ord-616e6714301d4dfa87f2652f15a6082aConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A stirred mixture of benzylsulfamic acid (73 g), PCl5 (81 g) in toluene (540 ml) is heated to 40°-50° C. for one hour and refluxed for about 3 hours. The cooled mixture is filtered through Celite and the filtrate concentrated in vacuo to remove the toluene affording the desired product as a liquid. is heated to 40°-50° C. for one hour refluxed for about 3 hours The cooled mixture is filtered through Celite the filtrate concentrated in vacuo to remove the toluene affording the desired product as a liquid
Source ID: ord-616e6714301d4dfa87f2652f15a6082aConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A solution of benzylsulfamoyl chloride (168 g) in anhydrous THF (300 ml) is added dropwise to a stirred solution of N-carbomethoxy-O-methylisourea (107 g) and triethylamine (90 g) in anhydrous THF (800 ml) under nitrogen at -70° C. The resulting suspension is warmed to RT, filtered and the filtrate evaporated in vacuo. The residue is partitioned between methylene chloride and 0.5N aq. HCl. The organic layer is dried, filtered, and concentrated in vacuo affording the desired product as an oil. filtered the filtrate evaporated in vacuo The residue is partitioned between methylene chloride and 0.5N aq. HCl The organic layer is dried filtered concentrated in vacuo
Source ID: ord-4099f6da5a8147cea0efd2977b40bde9Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A stirred mixture of benzylsulfamic acid (73 g), PCl5 (81 g) in toluene (540 ml) is heated to 40°-50° C. for one hour and refluxed for about 3 hours. The cooled mixture is filtered through Celite and the filtrate concentrated in vacuo to remove the toluene affording the desired product as a liquid. is heated to 40°-50° C. for one hour refluxed for about 3 hours The cooled mixture is filtered through Celite the filtrate concentrated in vacuo to remove the toluene affording the desired product as a liquid
Source ID: ord-616e6714301d4dfa87f2652f15a6082aConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A solution of benzylsulfamoyl chloride (168 g) in anhydrous THF (300 ml) is added dropwise to a stirred solution of N-carbomethoxy-O-methylisourea (107 g) and triethylamine (90 g) in anhydrous THF (800 ml) under nitrogen at -70° C. The resulting suspension is warmed to RT, filtered and the filtrate evaporated in vacuo. The residue is partitioned between methylene chloride and 0.5N aq. HCl. The organic layer is dried, filtered, and concentrated in vacuo affording the desired product as an oil. filtered the filtrate evaporated in vacuo The residue is partitioned between methylene chloride and 0.5N aq. HCl The organic layer is dried filtered concentrated in vacuo
Source ID: ord-7893914eec8143aa87ab92f4bb98fbddConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A stirred mixture of benzylsulfamic acid (73 g), PCl5 (81 g) in toluene (540 ml) is heated to 40°-50° C. for one hour and refluxed for about 3 hours. The cooled mixture is filtered through Celite and the filtrate concentrated in vacuo to remove the toluene affording the desired product as a liquid. is heated to 40°-50° C. for one hour refluxed for about 3 hours The cooled mixture is filtered through Celite the filtrate concentrated in vacuo to remove the toluene affording the desired product as a liquid
Source ID: ord-627aa5de39d34228b636c2bc32313be8Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A solution of benzylsulfamoyl chloride (168 g) in anhydrous THF (300 ml) is added dropwise to a stirred solution of N-carbomethoxy-O-methylisourea (107 g) and triethylamine (90 g) in anhydrous THF (800 ml) under nitrogen at -70° C. The resulting suspension is warmed to RT, filtered and the filtrate evaporated in vacuo. The residue is partitioned between methylene chloride and 0.5N aqueous HCl. The organic layer is dried, filtered, and concentrated in vacuo affording the desired product as an oil. filtered the filtrate evaporated in vacuo The residue is partitioned between methylene chloride and 0.5N aqueous HCl The organic layer is dried filtered concentrated in vacuo
Source ID: ord-62b52b96d75b476896011517204416baConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A solution of benzylsulfamoyl chloride (168 g) in anhydrous THF (300 ml) is added dropwise to a stirred solution of N-carbomethoxy-O-methylisourea (107 g) and triethylamine (90 g) in anhydrous THF (800 ml) under nitrogen at -70° C. The resulting suspension is warmed to RT, filtered and the filtrate evaporated in vacuo. The residue is partitioned between methylene chloride and 0.5N aq. HCl. The organic layer is dried, filtered, and concentrated in vacuo affording the desired product as an oil. filtered the filtrate evaporated in vacuo The residue is partitioned between methylene chloride and 0.5N aq. HCl The organic layer is dried filtered concentrated in vacuo
Source ID: ord-4099f6da5a8147cea0efd2977b40bde9PubChem References
These sources are listed in the compound's public database record.
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