No renderable structure data available
CCCCCCCCOC(=O)C(C)OChemical Intermediate
Structures, identifiers and computed properties have been matched to the database record by CAS.
| Intermediates | octyl 2-hydroxypropanoate |
|---|---|
| IUPAC Name | — |
| CAS Number | 5464-71-1 |
| Database ID | 95499 |
| Molecular Formula | — |
| Molecular Weight | — |
Product Information
octyl 2-hydroxypropanoate (CAS 5464-71-1) product identity, structure identifiers and related reaction data for chemical intermediate research and sourcing review.
Potential Applications
For professional research and industrial use only
Database ID 95499
Safety Notice
For professional research and industrial use only. Review the supplier safety data sheet before handling.
Synthesis data
12 reactions · 12 references
Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-13b1a209edd148498ea66446d4fd1490Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-13b1a209edd148498ea66446d4fd1490Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-13b1a209edd148498ea66446d4fd1490Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A 2 liter one neck round bottom flask equipped with a Dean Stark trap, condenser and nitrogen, inlet outlet was charged with 150.0 g (1.66 moles) lactic acid, 293.0 g (2.25 moles) octyl alcohol, 6 ml sulfuric acid and 500 ml toluene. Mixture was heated to 130° for 2.5 hours and water was collected as the reaction proceeded. The acid was neutralized by washing three times with 50 ml saturated sodium bicarbonate solution. Approximately 50 ml ether was needed to break the emulsion. The organic layer was collected and dried over magnesium sulfate. Octyl lactate was distilled under high vacuum to yield 119.85 g (35.6% yield) of clear colorless liquid. According to GC the product is 96.2% pure. Mixture was heated to 130° for 2.5 hours water was collected as the reaction by washing three times with 50 ml saturated sodium bicarbonate solution The organic layer was collected dried over magnesium sulfate Octyl lactate was distilled under high vacuum
Source ID: ord-12de98b0c10749cd9731aa5b85bad87eConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A 2 liter one neck round bottom flask equipped with a Dean Stark trap, condenser and nitrogen, inlet outlet was charged with 150.0 g (1.66 moles) lactic acid, 293.0 g (2.25 moles) octyl alcohol, 6 ml sulfuric acid and 500 ml toluene. Mixture was heated to 130° for 2.5 hours and water was collected as the reaction proceeded. The acid was neutralized by washing three times with 50 ml saturated sodium bicarbonate solution. Approximately 50 ml ether was needed to break the emulsion. The organic layer was collected and dried over magnesium sulfate. Octyl lactate was distilled under high vacuum to yield 119.85 g (35.6% yield) of clear colorless liquid. According to GC the product is 96.2% pure. Mixture was heated to 130° for 2.5 hours water was collected as the reaction by washing three times with 50 ml saturated sodium bicarbonate solution The organic layer was collected dried over magnesium sulfate Octyl lactate was distilled under high vacuum
Source ID: ord-12de98b0c10749cd9731aa5b85bad87eConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A 500 mL one neck round bottom flask equipped with a distillation apparatus and nitrogen inlet/outlet was charged with 100.0 g (0.847 moles) of ethyl lactate, 220.49 g (1.69 moles) of octyl alcohol and 0.423 g of sulfuric acid (based on 0.5 g sulfuric acid/one mole ethyl lactate). The reaction was refluxed for 8 hours and ethanol was collected as formed. The acid was neutralized by washing three times with 100 mL saturated sodium bicarbonate solution. Approximately 50 mL ether was needed to break the emulsion. The organic layer was collected and dried over magnesium sulfate. Excess octyl alcohol was removed by high vacuum distillation, and three fractional distillations led to 75.0 g (44% yield) of clear colorless oil. According to GC, the product is 95% pure. The reaction was refluxed for 8 hours ethanol was collected as formed by washing three times with 100 mL saturated sodium bicarbonate solution The organic layer was collected dried over magnesium sulfate Excess octyl alcohol was removed by high vacuum distillation, and three fractional distillations
Source ID: ord-f42ee048b59c4ef4b9e358aa8939591cConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A 500 mL one neck round bottom flask equipped with a distillation apparatus and nitrogen inlet/outlet was charged with 100.0 g (0.847 moles) of ethyl lactate, 220.49 g (1.69 moles) of octyl alcohol and 0.423 g of sulfuric acid (based on 0.5 g sulfuric acid/one mole ethyl lactate). The reaction was refluxed for 8 hours and ethanol was collected as formed. The acid was neutralized by washing three times with 100 mL saturated sodium bicarbonate solution. Approximately 50 mL ether was needed to break the emulsion. The organic layer was collected and dried over magnesium sulfate. Excess octyl alcohol was removed by high vacuum distillation, and three fractional distillations led to 75.0 g (44% yield) of clear colorless oil. According to GC, the product is 95% pure. The reaction was refluxed for 8 hours ethanol was collected as formed by washing three times with 100 mL saturated sodium bicarbonate solution The organic layer was collected dried over magnesium sulfate Excess octyl alcohol was removed by high vacuum distillation, and three fractional distillations
Source ID: ord-f42ee048b59c4ef4b9e358aa8939591cConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A 2 liter one neck round bottom flask equipped with a Dean Stark trap, condenser and nitrogen, inlet outlet was charged with 150.0 g (1.66 moles) lactic acid, 293.0 g (2.25 moles) octyl alcohol, 6 ml sulfuric acid and 500 ml toluene. Mixture was heated to 130° for 2.5 hours and water was collected as the reaction proceeded. The acid was neutralized by washing three times with 50 ml saturated sodium bicarbonate solution. Approximately 50 ml ether was needed to break the emulsion. The organic layer was collected and dried over magnesium sulfate. Octyl lactate was distilled under high vacuum to yield 119.85 g (35.6% yield) of clear colorless liquid. According to GC the product is 96.2% pure. Mixture was heated to 130° for 2.5 hours water was collected as the reaction by washing three times with 50 ml saturated sodium bicarbonate solution The organic layer was collected dried over magnesium sulfate Octyl lactate was distilled under high vacuum
Source ID: ord-12de98b0c10749cd9731aa5b85bad87eConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A 500 mL one neck round bottom flask equipped with a distillation apparatus and nitrogen inlet/outlet was charged with 100.0 g (0.847 moles) of ethyl lactate, 220.49 g (1.69 moles) of octyl alcohol and 0.423 g of sulfuric acid (based on 0.5 g sulfuric acid/one mole ethyl lactate). The reaction was refluxed for 8 hours and ethanol was collected as formed. The acid was neutralized by washing three times with 100 mL saturated sodium bicarbonate solution. Approximately 50 mL ether was needed to break the emulsion. The organic layer was collected and dried over magnesium sulfate. Excess octyl alcohol was removed by high vacuum distillation, and three fractional distillations led to 75.0 g (44% yield) of clear colorless oil. According to GC, the product is 95% pure. The reaction was refluxed for 8 hours ethanol was collected as formed by washing three times with 100 mL saturated sodium bicarbonate solution The organic layer was collected dried over magnesium sulfate Excess octyl alcohol was removed by high vacuum distillation, and three fractional distillations
Source ID: ord-f42ee048b59c4ef4b9e358aa8939591cConditions: temp:130.01; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A 2liter one neck round bottom flask equipped with a Dean Stark trap, condenser and nitrogen inlet/outlet was charged with 150.0 g (1.67 moles) lactic acid, 293.0 g (2.25 moles) octyl alcohol, 6 ml sulfuric acid and 500 ml toluene. Mixture was heated to 130° C. for 6 hours and water was collected as the reaction proceeded. The acid was neutralized by washing three times with 50 ml saturated sodium bicarbonate solution. The organic layer was collected and dried over magnesium sulfate. Octyl lactate was distilled under high vacuum to yield 119.9 g (35.6% yield) of clear colorless liquid. According to GC the product is 96.2% pure. water was collected as the reaction by washing three times with 50 ml saturated sodium bicarbonate solution The organic layer was collected dried over magnesium sulfate Octyl lactate was distilled under high vacuum
Source ID: ord-75fecda2e7cf42379438d65bd0f28772Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A 500 mL one neck round bottom flask equipped with a distillation apparatus and nitrogen inlet/outlet was charged with 100.0 g (0.85 moles) of ethyl lactate, 220.49 g (1.69 moles) of octyl alcohol and 0.42 g of sulfuric acid. The reaction was refluxed for 8 hours and ethanol was collected as formed. The acid was neutralized by washing three times with 100 mL saturated sodium bicarbonate solution. The organic layer was collected and dried over magnesium sulfate. Excess octyl alcohol was removed by high vacuum distillation, and three fractional distillations led to 75.0 g (44% yield) of clear colorless oil. According to GC, the product is 95% pure. The reaction was refluxed for 8 hours ethanol was collected as formed by washing three times with 100 mL saturated sodium bicarbonate solution The organic layer was collected dried over magnesium sulfate Excess octyl alcohol was removed by high vacuum distillation, and three fractional distillations
Source ID: ord-4523dfe2942d4f478458165c8af42eb4Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A 2 liter one neck round bottom flask equipped with a Dean Stark trap, condenser and nitrogen, inlet outlet was charged with 150.0 g (1.66 moles) lactic acid, 293.0 g (2.25 moles) octyl alcohol, 6 ml sulfuric acid and 500 ml toluene. Mixture was heated to 130° for 2.5 hours and water was collected as the reaction proceeded. The acid was neutralized by washing three times with 50 ml saturated sodium bicarbonate solution. Approximately 50 ml ether was needed to break the emulsion. The organic layer was collected and dried over magnesium sulfate. Octyl lactate was distilled under high vacuum to yield 119.85 g (35.6% yield) of clear colorless liquid. According to GC the product is 96.2% pure. Mixture was heated to 130° for 2.5 hours water was collected as the reaction by washing three times with 50 ml saturated sodium bicarbonate solution The organic layer was collected dried over magnesium sulfate Octyl lactate was distilled under high vacuum
Source ID: ord-12de98b0c10749cd9731aa5b85bad87ePubChem References
These sources are listed in the compound's public database record.
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