4-methylpiperidine;hydrochloride

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: The same procedure as in Example 1.5 is used. Thus, starting with 1,1-dimethylethyl [(S)-4-(5-aminopyrid-2-yl)-1-[(4-methylpiperid-1-yl)carbonyl]butyl]carbamate (10.2 g; 26.0 mmol), 9.5 g of 1-[(2S)-2-amino-5-(5-aminopyrid-2-yl)-1-oxopentyl[-4-methylpiperidine hydrochloride are obtained in the form of a hygroscopic amorphous powder, which is used without further purification in the following step. are obtained in the form of a hygroscopic amorphous powder, which is used without further purification in the following step