ethyl 2-(tert-butylamino)acetate

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: In analogy to the procedure described in Example 47 b), 6-cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (Example 1 b)) was reacted with ethyl 2-(tert-butylamino)acetate (CAN 37885-76-0) in the presence of TBTU and DIEA to obtain the title compound as colorless oil; MS (EI): m/e=426.5 [MH+].

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: In analogy to the procedure described in Example 47 b), 6-cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (Example 1 b)) was reacted with ethyl 2-(tert-butylamino)acetate (CAN 37885-76-0) in the presence of TBTU and DIEA to obtain the title compound as colorless oil; MS (EI): m/e=426.5 [MH+].

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: In analogy to the procedure described in Example 47 b), 6-cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (Example 1 b)) was reacted with ethyl 2-(tert-butylamino)acetate (CAN 37885-76-0) in the presence of TBTU and DIEA to obtain the title compound as colorless oil; MS (EI): m/e=426.5 [MH+].