N-dodecylaniline

Conditions: temp:0.00; pressure:0.00; stir:

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: A solution of α-tetralone (50 ml), dodecyl aniline (80 g) and benzene (150 ml) was refluxed in the presence of molecular sieve (100 g) with continuous removal of water. The crude product was crystallized from ethanol to give N-(1,2,3,4-tetrahydronaphthylidene) aniline (XXVI). XXVI had a melting point of 53° C. The crude product was crystallized from ethanol

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: N-dodecylaminobenzene was prepared from the N-dodecanoylaminobenzene of (a) by reduction with diborane by a procedure similar to that of Example 1(b). A yield of 74% of white crystals from hexane, m.p. 26.7°-27.2° C. was obtained.

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: According to the method described in example S40a, (R)-benzyl 3-amino-4-(dimethylamino)butanoate is reacted with of triphosgene and N-dodecylaniline to yield (R)-benzyl 4-(dimethylamino)-3-(3-dodecyl-3-phenylureido)butanoate. According to the methods described in example S40b,c the preceding benzyl ester is converted to the title compound.

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: A solution of α-tetralone (50 ml), dodecyl aniline (80 g) and benzene (150 ml) was refluxed in the presence of molecular sieve (100 g) with continuous removal of water. The crude product was crystallized from ethanol to give N-(1,2,3,4-tetrahydronaphthylidene) aniline (XXVI). XXVI had a melting point of 53° C. The crude product was crystallized from ethanol

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: N-dodecylaminobenzene was prepared from the N-dodecanoylaminobenzene of (a) by reduction with diborane by a procedure similar to that of Example 1(b). A yield of 74% of white crystals from hexane, m.p. 26.7°-27.2° C. was obtained.