N-methyl-3-oxo-N-phenylbutanamide

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: To a solution of N-methyl-3-oxo-N-phenylbutanamide (26.0 g, 0.136 mol) in carbon tetrachloride (200 ml) was added bromine (24.05 g, 0.15 mol) dropwise over 30 min, and the mixture was heated under reflux for 5 min. After allowing to cool to room temperature, the reaction mixture was concentrated in vacuo, triturated with diethyl ether and filtered to afford the title compound as a white solid (10.3 g, 28%). the mixture was heated under reflux for 5 min the reaction mixture was concentrated in vacuo triturated with diethyl ether filtered

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: To a solution of N-methyl-3-oxo-N-phenylbutanamide (26.0 g, 0.136 mol) in carbon tetrachloride (200 ml) was added bromine (24.05 g, 0.15 mol) dropwise over 30 min, and the mixture was heated under reflux for 5 min. After allowing to cool to room temperature, the reaction mixture was concentrated in vacuo, triturated with diethyl ether and filtered to afford the title compound as a white solid (10.3 g, 28%). the mixture was heated under reflux for 5 min the reaction mixture was concentrated in vacuo triturated with diethyl ether filtered

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: To a solution of N-methyl-3-oxo-N-phenylbutanamide (26.0 g, 0.136 mol) in carbon tetrachloride (200 ml) was added bromine (24.05 g, 0.15 mol) dropwise over 30 min, and the mixture was heated under reflux for 5 min. After allowing to cool to room temperature, the reaction mixture was concentrated in vacuo, triturated with diethyl ether and filtered to afford the title compound as a white solid (10.3 g, 28%). the mixture was heated under reflux for 5 min the reaction mixture was concentrated in vacuo triturated with diethyl ether filtered

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: To a solution of N-methyl-3-oxo-N-phenylbutanamide (26.0 g, 0.136 mol) in carbon tetrachloride (200 ml) was added bromine (24.05 g, 0.15 mol) dropwise over 30 min, and the mixture was heated under reflux for 5 min. After allowing to cool to room temperature, the reaction mixture was concentrated in vacuo, triturated with diethyl ether and filtered to afford the title compound as a white solid (10.3 g, 28%). the mixture was heated under reflux for 5 min the reaction mixture was concentrated in vacuo triturated with diethyl ether filtered