1-chloro-4-diethoxyphosphorylbenzene

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: 3.5 g (15 mmol) of diethyl(4-chlorophenyl)-phosphonate and 3 ml (24.7 mmol) of n-pentylbromide are heated to 150° C. for 90 minutes with stirring. The cooled clear solution is chromatographed on silica gel and eluted with cyclohexane/ethyl acetate (7:3 to 1:1). The cooled clear solution is chromatographed on silica gel eluted with cyclohexane/ethyl acetate (7:3 to 1:1)