5-isothiocyanatopentan-1-ol

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: The synthesis method of Example 1-(3) was applied. 3-Amino-1H-1,2,4-triazole (4.00 g), dimethylformamide (25 ml) and 5-hydroxypentyl isothiocyanate (9.24 g) were used as reagents. After the reaction, silica gel column chromatography (chloroform-methanol) was applied to give 2.06 g of white crystals (yield 19%). The crystals were subjected to recrystallization from chloroform to give white crystals.

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: The synthesis method of Example 45-(1) was applied. 5-Hydroxypentylamine (6.00 g), carbon disulfide (40 ml), triethylamine (8.3 ml), ethyl chlorocarbonate (5.4 ml), triethylamine (8.3 ml) and chloroform (20 ml) were used as reagents. After the reaction, a yellow liquid was quantitatively obtained. The synthesis method of Example 45-(1) After the reaction a yellow liquid was quantitatively obtained