(1S)-1-(4-chlorophenyl)propan-1-amine

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: The title compound is prepared from (9-hydroxy-3,3-dimethyl-1,5-dioxa-spiro[5.5]undec-9-yl)-acetaldehyde and (S)-1-(4-chloro-phenyl)-propylamine following a procedure analogous to that described in Step 3 of Intermediate 2. Yield: 60% of theory; LC (method 5): tR=1.15 min; Mass spectrum (ESI+): m/z=396/398 (Cl) [M+H]+.