1-(oxolan-3-ylmethyl)piperidin-4-amine

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: 2-Chloro-6-[4-(1-3-tetrahydrofuranyl)methyl)piperidinylamino]-9-cyclopentylpurine is prepared from 2,6-dichloro-9-cyclopentylpurine, 4amino-1-(3-tetrahydrofuranylmethyl)piperidine, and triethylamine essentially as described above in Example 1, Scheme A, step b.

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: 2-Chloro-6-[4-(1-3-tetrahydrofuranyl)methyl)piperidinylamino]-9-cyclopentylpurine is prepared from 2,6-dichloro-9-cyclopentylpurine, 4amino-1-(3-tetrahydrofuranylmethyl)piperidine, and triethylamine essentially as described above in Example 1, Scheme A, step b.

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: 2-Chloro-6-[4-(1-3-tetrahydrofuranyl)methyl)piperidinylamino]-9-cyclopentylpurine is prepared from 2,6-dichloro-9-cyclopentylpurine, 4amino-1-(3-tetrahydrofuranylmethyl)piperidine, and triethylamine essentially as described above in Example 1, Scheme A, step b.