1-(2-methylsulfanylphenyl)piperazine

Conditions: temp:0.00; pressure:0.00; stir:

Conditions: temp:70.01; pressure:0.00; stir:

Procedure: Dilution of the aliquot (2 uL) with DMSO (200 uL).

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: Phenyl N-(2-methylquinolin-3-yl)carbamate and 1-(2-methylthiophenyl)piperazine were reacted by the same way with the example 114 to obtain the titled compound.

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: Phenyl N-(2-methoxyquinolin-3-yl)carbamate and 1-(2-methylthiophenyl)piperazine were reacted by the same way with the example 81 to obtain the titled compound.

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: Phenyl N-(5-ethyl-6-methyl-2-methoxypyridin-3-yl)carbamate and 1-(2-methylthiophenyl)piperazine were reacted by the same way with the example 1 to obtain the titled compound.

Conditions: temp:0.00; pressure:0.00; stir:

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: 4-(2-methylthiophenyl)-1-[3-(5,6,7,8-tetrahydronaphth-1-yloxy)-prop-1-yl]-piperazine from 1-(5,6,7,8-tetrahydronaphth-1-yloxy)-3-bromopropane and 1-(2-methylthiophenyl)-piperazine; yield 64% of theory; m.p. of the hydrochloride 224°-225°C. decomp.); 4-(3-trifluoromethylphenyl)-1-[3-(5,6,7,8-tetrahydronaphth-1-yloxy)-prop-1-yl]-piperazine from 1-(5,6,7,8-tetrahydro-napth-1-yloxy)-3-bromopropane and 1-(3-trifluoromethylphenyl)-piperazine; yield 84% of theory; m.p. of the dihydrochloride: 182°-183°C. 182°-183°C.

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: 4-(2-methylthiophenyl)-1-[3-(5,6,7,8-tetrahydronaphth-1-yloxy)-prop-1-yl]-piperazine from 1-(5,6,7,8-tetrahydronaphth-1-yloxy)-3-bromopropane and 1-(2-methylthiophenyl)-piperazine; yield 64% of theory; m.p. of the hydrochloride 224°-225°C. decomp.); 4-(3-trifluoromethylphenyl)-1-[3-(5,6,7,8-tetrahydronaphth-1-yloxy)-prop-1-yl]-piperazine from 1-(5,6,7,8-tetrahydro-napth-1-yloxy)-3-bromopropane and 1-(3-trifluoromethylphenyl)-piperazine; yield 84% of theory; m.p. of the dihydrochloride: 182°-183°C. 182°-183°C.

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: Phenyl N-(2-methylquinolin-3-yl)carbamate and 1-(2-methylthiophenyl)piperazine were reacted by the same way with the example 114 to obtain the titled compound.

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: Phenyl N-(2-methoxyquinolin-3-yl)carbamate and 1-(2-methylthiophenyl)piperazine were reacted by the same way with the example 81 to obtain the titled compound.

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: Phenyl N-(5-ethyl-6-methyl-2-methoxypyridin-3-yl)carbamate and 1-(2-methylthiophenyl)piperazine were reacted by the same way with the example 1 to obtain the titled compound.

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: Phenyl N-(5-ethyl-6-methyl-2-methoxypyridin-3-yl)carbamate and 1-(2-methylthiophenyl)piperazine were reacted by the same way with the example 1 to obtain the titled compound.