No renderable structure data available
CS(=O)(=O)C1=CC(=C(C=C1)Br)NChemical Intermediate
Structures, identifiers and computed properties have been matched to the database record by CAS.
| Intermediates | 2-bromo-5-methylsulfonylaniline |
|---|---|
| IUPAC Name | — |
| CAS Number | 942474-24-0 |
| Database ID | 26597513 |
| Molecular Formula | — |
| Molecular Weight | — |
Product Information
2-bromo-5-methylsulfonylaniline (CAS 942474-24-0) product identity, structure identifiers and related reaction data for chemical intermediate research and sourcing review.
Potential Applications
For professional research and industrial use only
Database ID 26597513
Safety Notice
For professional research and industrial use only. Review the supplier safety data sheet before handling.
Synthesis data
8 reactions · 8 references
Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-0b084ab81c384fb580a83bf4a8d1f30aConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A solution of 1-bromo-4-(methylsulfonyl)-2-nitrobenzene (1.0 eq.), iron powder (3.0 eq.), and concentrated HCl (1.04 eq.) were mixed together in ethanol (0.64 M) and heated to reflux. The reaction was stirred for 24 hours, and the solvent was evaporated. The resulting residue was diluted with ethyl acetate and saturated aqueous ammonium chloride solution. The aqueous layer was extracted three times with ethyl acetate, and the combined organic layers were washed with water, brine, dried over anhydrous MgSO4, and concentrated en vacuo. The crude material was purified by triturating in 1:1 hexane/ether to give a light yellow solid. heated to reflux the solvent was evaporated The resulting residue was diluted with ethyl acetate and saturated aqueous ammonium chloride solution The aqueous layer was extracted three times with ethyl acetate the combined organic layers were washed with water, brine dried over anhydrous MgSO4 concentrated en vacuo The crude material was purified by triturating in 1:1 hexane/ether to give a light yellow solid
Source ID: ord-87f6278c5290492991fbc10d08b8a5a1Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A solution of 1-bromo-4-(methylsulfonyl)-2-nitrobenzene (1.0 eq.), iron powder (3.0 eq.), and concentrated HCl (1.04 eq.) were mixed together in ethanol (0.64 M) and heated to reflux. The reaction was stirred for 24 hours, and the solvent was evaporated. The resulting residue was diluted with ethyl acetate and saturated aqueous ammonium chloride solution. The aqueous layer was extracted three times with ethyl acetate, and the combined organic layers were washed with water, brine, dried over anhydrous MgSO4, and concentrated en vacuo. The crude material was purified by triturating in 1:1 hexane/ether to give a light yellow solid. heated to reflux the solvent was evaporated The resulting residue was diluted with ethyl acetate and saturated aqueous ammonium chloride solution The aqueous layer was extracted three times with ethyl acetate the combined organic layers were washed with water, brine dried over anhydrous MgSO4 concentrated en vacuo The crude material was purified by triturating in 1:1 hexane/ether to give a light yellow solid
Source ID: ord-87f6278c5290492991fbc10d08b8a5a1Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A solution of 1-bromo-4-(methylsulfonyl)-2-nitrobenzene (1.0 eq.), iron powder (3.0 eq.), and concentrated HCl (1.04 eq.) were mixed together in ethanol (0.64 M) and heated to reflux. The reaction was stirred for 24 hours, and the solvent was evaporated. The resulting residue was diluted with ethyl acetate and saturated aqueous ammonium chloride solution. The aqueous layer was extracted three times with ethyl acetate, and the combined organic layers were washed with water, brine, dried over anhydrous MgSO4, and concentrated en vacuo. The crude material was purified by triturating in 1:1 hexane/ether to give a light yellow solid. heated to reflux the solvent was evaporated The resulting residue was diluted with ethyl acetate and saturated aqueous ammonium chloride solution The aqueous layer was extracted three times with ethyl acetate the combined organic layers were washed with water, brine dried over anhydrous MgSO4 concentrated en vacuo The crude material was purified by triturating in 1:1 hexane/ether to give a light yellow solid
Source ID: ord-87f6278c5290492991fbc10d08b8a5a1Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-0b084ab81c384fb580a83bf4a8d1f30aConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A solution of 1-bromo-4-(methylsulfonyl)-2-nitrobenzene (1.0 eq.), iron powder (3.0 eq.), and concentrated HCl (1.04 eq.) were mixed together in ethanol (0.64 M) and heated to reflux. The reaction was stirred for 24 hours, and the solvent was evaporated. The resulting residue was diluted with ethyl acetate and saturated aqueous ammonium chloride solution. The aqueous layer was extracted three times with ethyl acetate, and the combined organic layers were washed with water, brine, dried over anhydrous MgSO4, and concentrated en vacuo. The crude material was purified by triturating in 1:1 hexane/ether to give a light yellow solid. heated to reflux the solvent was evaporated The resulting residue was diluted with ethyl acetate and saturated aqueous ammonium chloride solution The aqueous layer was extracted three times with ethyl acetate the combined organic layers were washed with water, brine dried over anhydrous MgSO4 concentrated en vacuo The crude material was purified by triturating in 1:1 hexane/ether to give a light yellow solid
Source ID: ord-834dc3f4fc91428ca2fdad939da807c4Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A solution of 1-bromo-4-(methylsulfonyl)-2-nitrobenzene (1.0 eq.), iron powder (3.0 eq.), and concentrated HCl (1.04 eq.) were mixed together in ethanol (0.64 M) and heated to reflux. The reaction was stirred for 24 hours, and the solvent was evaporated. The resulting residue was diluted with ethyl acetate and saturated aqueous ammonium chloride solution. The aqueous layer was extracted three times with ethyl acetate, and the combined organic layers were washed with water, brine, dried over anhydrous MgSO4, and concentrated en vacuo. The crude material was purified by triturating in 1:1 hexane/ether to give a light yellow solid. heated to reflux the solvent was evaporated The resulting residue was diluted with ethyl acetate and saturated aqueous ammonium chloride solution The aqueous layer was extracted three times with ethyl acetate the combined organic layers were washed with water, brine dried over anhydrous MgSO4 concentrated en vacuo The crude material was purified by triturating in 1:1 hexane/ether to give a light yellow solid
Source ID: ord-2a47feca8214474db38864ed1aca8526Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A solution of 1-bromo-4-(methylsulfonyl)-2-nitrobenzene (1.0 eq.), iron powder (3.0 eq.), and concentrated HCl (1.04 eq.) were mixed together in ethanol (0.64 M) and heated to reflux. The reaction was stirred for 24 hours, and the solvent was evaporated. The resulting residue was diluted with ethyl acetate and saturated aqueous ammonium chloride solution. The aqueous layer was extracted three times with ethyl acetate, and the combined organic layers were washed with water, brine, dried over anhydrous MgSO4, and concentrated en vacuo. The crude material was purified by triturating in 1:1 hexane/ether to give a light yellow solid. heated to reflux the solvent was evaporated The resulting residue was diluted with ethyl acetate and saturated aqueous ammonium chloride solution The aqueous layer was extracted three times with ethyl acetate the combined organic layers were washed with water, brine dried over anhydrous MgSO4 concentrated en vacuo The crude material was purified by triturating in 1:1 hexane/ether to give a light yellow solid
Source ID: ord-87f6278c5290492991fbc10d08b8a5a1PubChem References
These sources are listed in the compound's public database record.
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