No renderable structure data available
CCOC(=O)C1=C(C=CC=C1Cl)ClChemical Intermediate
Structures, identifiers and computed properties have been matched to the database record by CAS.
| Intermediates | ethyl 2,6-dichlorobenzoate |
|---|---|
| IUPAC Name | — |
| CAS Number | 81055-73-4 |
| Database ID | 2737439 |
| Molecular Formula | — |
| Molecular Weight | — |
Product Information
ethyl 2,6-dichlorobenzoate (CAS 81055-73-4) product identity, structure identifiers and related reaction data for chemical intermediate research and sourcing review.
Potential Applications
For professional research and industrial use only
Database ID 2737439
Safety Notice
For professional research and industrial use only. Review the supplier safety data sheet before handling.
Synthesis data
12 reactions · 12 references
Conditions: temp:80.01; pressure:0.00; stir:
Source ID: ord-b6f521ab28104423bea4bf25d7f5b059Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-31d0d0b507a44b629461ae0201ec63f2Conditions: temp:-78.01; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: n-Butyllithium (2.5M in hexane, 16.5 ml) was added to a solution of ethyl 2,6-dichlorobenzoate (6.89 g) in THF while maintaining the temperature below -70° C. The mixture was stirred at -78° C. for 1 hour and poured onto solid carbon dioxide pellets. The mixture was acidified to pH1 and extracted with ether, washed with water, dried (MgSO4) and filtered. The filtrate was evaporated to dryness and the residue was recrystallized from a mixture of cyclohexane and ether to give 2,4-dichloro-3-ethoxycarbonylbenzoic acid (4.35 g) as a white solid mp 168° C. while maintaining the temperature below -70° C extracted with ether washed with water dried (MgSO4) filtered The filtrate was evaporated to dryness the residue was recrystallized from a mixture of cyclohexane and ether
Source ID: ord-5dbbeaec91b24991903be26d32e82eecConditions: temp:-78.01; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: n-Butyllithium (2.5M in hexane, 16.5 ml) was added to a solution of ethyl 2,6-dichlorobenzoate (6.89 g) in THF while maintaining the temperature below -70° C. The mixture was stirred at -78° C. for 1 hour and poured onto solid carbon dioxide pellets. The mixture was acidified to pH1 and extracted with ether, washed with water, dried (MgSO4) and filtered. The filtrate was evaporated to dryness and the residue was recrystallized from a mixture of cyclohexane and ether to give 2,4-dichloro-3-ethoxycarbonylbenzoic acid (4.35 g) as a white solid mp 168° C. while maintaining the temperature below -70° C extracted with ether washed with water dried (MgSO4) filtered The filtrate was evaporated to dryness the residue was recrystallized from a mixture of cyclohexane and ether
Source ID: ord-9b8ac4aff151498ebb926ebb49065b1dConditions: temp:-78.01; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: n-Butyllithium (2.5M in hexane, 16.5 ml) was added to a solution of ethyl 2,6-dichlorobenzoate (6.89 g) in THF while maintaining the temperature below -70° C. The mixture was stirred at -78° C. for 1 hour and poured onto solid carbon dioxide pellets. The mixture was acidified to pH1 and extracted with ether, washed with water, dried (MgSO4) and filtered. The filtrate was evaporated to dryness and the residue was recrystallized from a mixture of cyclohexane and ether to give 2,4-dichloro-3-ethoxycarbonylbenzoic acid (4.35 g) as a white solid mp 168° C. while maintaining the temperature below -70° C extracted with ether washed with water dried (MgSO4) filtered The filtrate was evaporated to dryness the residue was recrystallized from a mixture of cyclohexane and ether
Source ID: ord-9b8ac4aff151498ebb926ebb49065b1dConditions: temp:-78.01; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: n-Butyllithium (2.5M in hexane, 16.5 ml) was added to a solution of ethyl 2,6-dichlorobenzoate (6.89 g) in THF while maintaining the temperature below -70° C. The mixture was stirred at -78° C. for 1 hour and poured onto solid carbon dioxide pellets. The mixture was acidified to pH1 and extracted with ether, washed with water, dried (MgSO4) and filtered. The filtrate was evaporated to dryness and the residue was recrystallized from a mixture of cyclohexane and ether to give 2,4-dichloro-3-ethoxycarbonylbenzoic acid (4.35 g) as a white solid mp 168° C. while maintaining the temperature below -70° C extracted with ether washed with water dried (MgSO4) filtered The filtrate was evaporated to dryness the residue was recrystallized from a mixture of cyclohexane and ether
Source ID: ord-5dbbeaec91b24991903be26d32e82eecConditions: temp:-78.01; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: n-Butyllithium (2.5M in hexane, 16.5 ml) was added to a solution of ethyl 2,6-dichlorobenzoate (6.89 g) in THF while maintaining the temperature below -70° C. The mixture was stirred at -78° C. for 1 hour and poured onto solid carbon dioxide pellets. The mixture was acidified to pH1 and extracted with ether, washed with water, dried (MgSO4) and filtered. The filtrate was evaporated to dryness and the residue was recrystallized from a mixture of cyclohexane and ether to give 2,4-dichloro-3-ethoxycarbonylbenzoic acid (4.35 g) as a white solid mp 168° C. while maintaining the temperature below -70° C extracted with ether washed with water dried (MgSO4) filtered The filtrate was evaporated to dryness the residue was recrystallized from a mixture of cyclohexane and ether
Source ID: ord-9b8ac4aff151498ebb926ebb49065b1dConditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-31d0d0b507a44b629461ae0201ec63f2Conditions: temp:-78.01; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: n-Butyllithium (2.5M in hexane, 16.5 ml) was added to a solution of ethyl 2,6-dichlorobenzoate (6.89 g) in THF while maintaining the temperature below -70° C. The mixture was stirred at -78° C. for 1 hour and poured onto solid carbon dioxide pellets. The mixture was acidified to pill and extracted with ether, washed with water, dried (MgSO4) and filtered. The filtrate was evaporated to dryness and the residue was recrystallized from a mixture of cyclohexane and ether to give 2,4-dichloro-3-ethoxycarbonylbenzoic acid (4.35 g) as a white solid mp 168° C. while maintaining the temperature below -70° C extracted with ether washed with water dried (MgSO4) filtered The filtrate was evaporated to dryness the residue was recrystallized from a mixture of cyclohexane and ether
Source ID: ord-1caa32a47b49450aaa94f037f8a67b69Conditions: temp:-78.01; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: n-Butyllithium (2.5M in hexane, 16.5 ml) was added to a solution of ethyl 2,6-dichlorobenzoate (6.89 g) in THF while maintaining the temperature below -70° C. The mixture was stirred at -78° C. for 1 hour and poured onto solid carbon dioxide pellets. The mixture was acidified to pill and extracted with ether, washed with water, dried (MgSO4) and filtered. The filtrate was evaporated to dryness and the residue was recrystallized from a mixture of cyclohexane and ether to give 2,4-dichloro-3-ethoxycarbonylbenzoic acid (4.35 g) as a white solid mp 168° C. while maintaining the temperature below -70° C extracted with ether washed with water dried (MgSO4) filtered The filtrate was evaporated to dryness the residue was recrystallized from a mixture of cyclohexane and ether
Source ID: ord-1caa32a47b49450aaa94f037f8a67b69Conditions: temp:-78.01; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: n-Butyllithium (2.5 M in hexane, 16.5 ml) was added to a solution of ethyl 2,6-dichlorobenzoate (6.89 g) in THF while maintaining the temperature below -70° C. The mixture was stirred at -78° C. for 1 hour and poured onto solid carbon dioxide pellets. The mixture was acidified to pH1 and extracted with ether, washed with water, dried (MgSO4) and filtered. The filtrate was evaporated to dryness and the residue was recrystallized from a mixture of cyclohexane and ether to give 2,4-dichloro-3-ethoxycarbonylbenzoic acid (435 g) a s a white solid mp 168° C. while maintaining the temperature below -70° C extracted with ether washed with water dried (MgSO4) filtered The filtrate was evaporated to dryness the residue was recrystallized from a mixture of cyclohexane and ether
Source ID: ord-3146af1be07448fbae86da8efcd11f75Conditions: temp:-78.01; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: n-Butyllithium (2.5M in hexane, 16.5 ml) was added to a solution of ethyl 2,6-dichlorobenzoate (6.89 g) in THF while maintaining the temperature below -70° C. The mixture was stirred at -78° C. for 1 hour and poured onto solid carbon dioxide pellets. The mixture was acidified to pH1 and extracted with ether, washed with water, dried (MgSO4) and filtered. The filtrate was evaporated to dryness and the residue was recrystallized from a mixture of cyclohexane and ether to give 2,4-dichloro-3-ethoxycarbonylbenzoic acid (4.35 g) as a white solid mp 168° C. while maintaining the temperature below -70° C extracted with ether washed with water dried (MgSO4) filtered The filtrate was evaporated to dryness the residue was recrystallized from a mixture of cyclohexane and ether
Source ID: ord-5dbbeaec91b24991903be26d32e82eecPubChem References
These sources are listed in the compound's public database record.
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