2-chlorocycloheptan-1-one

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: From 2-chlorocycloheptanone and 5-(benzyloxy)-3H-imidazo[4,5-b]pyridine, prepared in a similar manner as the one described in Example 1.11, the title compound was obtained. LCMS m/z=246.1 [M+H]+; 1H NMR (400 MHz, DMSO-d6) δ ppm 1.40-1.50 (m, 1H), 1.70-2.10 (m, 5H), 2.25-2.40 (m, 2H), 2.55-2.65 (m, 1H), 2.75-2.85 (m, 1H), 5.67 (dd, J1=9.5 Hz, J2=4.3 Hz, 1H), 6.77 (d, J=8.7 Hz, 1H), 8.08 (d, J=8.7 Hz, 1H), 8.88 (s, 1H).