2,4-dimethylbenzamide

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: A suspension of 29 g (0.19 mole) of 2,4-dimethylbenzamide, 40.5 g (0.19 mole) of phosphorus pentachloride and 300 ml of AR carbon tetrachloride was heated at 70° for 30 min. The solution was cooled to 30° and 9.2 g (0.19 mole) of 97% formic acid added dropwise. Stirring was continued for another 20 min., then the product was collected by filtration, washed with AR carbon tetrachloride and air-dried to give 30.5 g, m.p. decomposes upon standing. was heated at 70° for 30 min The solution was cooled to 30° the product was collected by filtration washed with AR carbon tetrachloride air-dried to give 30.5 g

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: Saturated with anhydrous ammonia, a solution of 50 g (0.3 mole) of 2,4-dimethylbenzoyl chloride and 500 ml of AR chloroform, while maintaining a temperature of 15°. Stirred for 20 min., then filtered, washed with cold distilled water and oven-dried at 60° to give 29.1 g, m.p. 184°-186°. filtered washed with cold distilled water oven-dried at 60° to give 29.1 g, m.p. 184°-186°