methyl 2,4-bis(bromomethyl)benzoate

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: According to a similar procedure to that described in Example 1-(5), methyl 2,4-bis(bromomethyl)benzoate (described in Chem. Ber., 127, 2081 (1994); 13.3 g, 41.3 mmol) and sodium acetate (16.4 g, 200 mmol) were reacted, and the reaction mixture was worked up to afford, after extraction, the title compound as a crude product. The crude product was subjected to chromatography on a silica gel (200 g) column (eluent; ethyl acetate:hexane=3:17˜3:5) to afford the title compound (6.35 g, 55% yield) as an oil. to afford after extraction