2-(3-methylbutanoyl)cyclohexan-1-one

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: Compound IVd is obtained in 90% yield as a pale yellow liquid, according to Example 4, from 4-cyclohex-1-enyl-morpholine (82.64 g, 0.5 mol, obtained in Example 1), triethylamine (71.34 g, 0.71 mol), isovaleryl chloride (85.01 g, 0.71 mol), toluene (760 mL) and 20% aqueous HCl (166 mL). Compound IVd is obtained in 90% yield as a pale yellow liquid

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: Compound IVd is obtained in 90% yield as a pale yellow liquid, according to Example 4, from 4-cyclohex-1-enyl-morpholine (82.64 g, 0.5 mol, obtained in Example 1), triethylamine (71.34 g, 0.71 mol), isovaleryl chloride (85.01 g, 0.71 mol), toluene (760 mL) and 20% aqueous HCl (166 mL). Compound IVd is obtained in 90% yield as a pale yellow liquid