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C1(C)OCCO1Chemical Intermediate
Structures, identifiers and computed properties have been matched to the database record by CAS.
| Intermediates | 2-methyl-1,3-dioxolane |
|---|---|
| IUPAC Name | — |
| CAS Number | 497-26-7 |
| Database ID | 10342 |
| Molecular Formula | — |
| Molecular Weight | — |
Product Information
2-methyl-1,3-dioxolane (CAS 497-26-7) product identity, structure identifiers and related reaction data for chemical intermediate research and sourcing review.
Potential Applications
For professional research and industrial use only
Database ID 10342
Safety Notice
For professional research and industrial use only. Review the supplier safety data sheet before handling.
Synthesis data
10 reactions · 10 references
Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-409627ab10924c79af0c4a9273ce61cfConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: To a mixture of 2-methyl dioxolane (0.897 ml, 10 mmol) and azidotrimethylsilane (1.6 ml, 12 mmol) was added SnCl4 (40 μl) at −78° C. After addition, the cooling bath was removed and the reaction was warmed up to room temperature. After 1 hr, the reaction was worked up by partitioning between DCM (50 ml) and saturated aqueous NaHCO3 (50 ml). The aqueous layer was further extracted with DCM (20 ml). All the DCM extracts were combined, dried over MgSO4 and evaporated under reduced pressure. The residue was dissolved in 10% aqueous methanol. After 2 hr at room temperature, all the solvents were removed under reduced pressure. The title compound was obtained as a colourless oil (224 mg, 17.1%). After addition the cooling bath was removed by partitioning between DCM (50 ml) and saturated aqueous NaHCO3 (50 ml) The aqueous layer was further extracted with DCM (20 ml) dried over MgSO4 evaporated under reduced pressure The residue was dissolved in 10% aqueous methanol After 2 hr at room temperature all the solvents were removed under reduced pressure
Source ID: ord-a093ce7ab5824dc8ab5a5b03f983fb6dConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: To a mixture of 2-methyl dioxolane (0.897 ml, 10 mmol) and azidotrimethylsilane (1.6 ml, 12 mmol) was added SnCl4 (40 μl) at −78° C. After addition, the cooling bath was removed and the reaction was warmed up to room temperature. After 1 hr, the reaction was worked up by partitioning between DCM (50 ml) and saturated aqueous NaHCO3 (50 ml). The aqueous layer was further extracted with DCM (20 ml). All the DCM extracts were combined, dried over MgSO4 and evaporated under reduced pressure. The residue was dissolved in 10% aqueous methanol. After 2 hr at room temperature, all the solvents were removed under reduced pressure. The title compound was obtained as a colourless oil (224 mg, 17.1%). After addition the cooling bath was removed by partitioning between DCM (50 ml) and saturated aqueous NaHCO3 (50 ml) The aqueous layer was further extracted with DCM (20 ml) dried over MgSO4 evaporated under reduced pressure The residue was dissolved in 10% aqueous methanol After 2 hr at room temperature all the solvents were removed under reduced pressure
Source ID: ord-a093ce7ab5824dc8ab5a5b03f983fb6dConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: To a mixture of 2-methyl dioxolane (0.897 ml, 10 mmol) and azidotrimethylsilane (1.6 ml, 12 mmol) was added SnCl4 (40 μl) at −78° C. After addition, the cooling bath was removed and the reaction was warmed up to room temperature. After 1 hr, the reaction was worked, up by partitioning between DCM (50 ml) and saturated aqueous NaHCO3 (50 ml). The aqueous layer was further extracted with DCM (20 ml). All the DCM extracts were combined, dried over MgSO4 and evaporated under reduced pressure. The residue was dissolved in 10% aqueous methanol. After 2 hr at room temperature, all the solvents were removed under reduced pressure. The title compound was obtained as a colourless oil (224 mg, 17.1%). After addition the cooling bath was removed up by partitioning between DCM (50 ml) and saturated aqueous NaHCO3 (50 ml) The aqueous layer was further extracted with DCM (20 ml) dried over MgSO4 evaporated under reduced pressure The residue was dissolved in 10% aqueous methanol After 2 hr at room temperature all the solvents were removed under reduced pressure
Source ID: ord-6728cc1d00ba42d5aaf92e5232a5e345Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: To a mixture of 2-methyl dioxolane (0.897 ml, 10 mmol) and azidotrimethylsilane (1.6 ml, 12 mmol) was added SnCl4 (40 μl) at −78° C. After addition, the cooling bath was removed and the reaction was warmed up to room temperature. After 1 hr, the reaction was worked, up by partitioning between DCM (50 ml) and saturated aqueous NaHCO3 (50 ml). The aqueous layer was further extracted with DCM (20 ml). All the DCM extracts were combined, dried over MgSO4 and evaporated under reduced pressure. The residue was dissolved in 10% aqueous methanol. After 2 hr at room temperature, all the solvents were removed under reduced pressure. The title compound was obtained as a colourless oil (224 mg, 17.1%). After addition the cooling bath was removed up by partitioning between DCM (50 ml) and saturated aqueous NaHCO3 (50 ml) The aqueous layer was further extracted with DCM (20 ml) dried over MgSO4 evaporated under reduced pressure The residue was dissolved in 10% aqueous methanol After 2 hr at room temperature all the solvents were removed under reduced pressure
Source ID: ord-6728cc1d00ba42d5aaf92e5232a5e345Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: To a mixture of 2-methyl dioxolane (0.897 ml, 10 mmol) and azidotrimethylsilane (1.6 ml, 12 mmol) was added SnCl4 (40 μl) at −78° C. After addition, the cooling bath was removed and the reaction was warmed up to room temperature. After 1 hr, the reaction was worked, up by partitioning between DCM (50 ml) and saturated aqueous NaHCO3 (50 ml). The aqueous layer was further extracted with DCM (20 ml). All the DCM extracts were combined, dried over MgSO4 and evaporated under reduced pressure. The residue was dissolved in 10% aqueous methanol. After 2 hr at room temperature, all the solvents were removed under reduced pressure. The title compound was obtained as a colourless oil (224 mg, 17.1%). After addition the cooling bath was removed up by partitioning between DCM (50 ml) and saturated aqueous NaHCO3 (50 ml) The aqueous layer was further extracted with DCM (20 ml) dried over MgSO4 evaporated under reduced pressure The residue was dissolved in 10% aqueous methanol After 2 hr at room temperature all the solvents were removed under reduced pressure
Source ID: ord-6728cc1d00ba42d5aaf92e5232a5e345Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: To a mixture of 2-methyl dioxolane (0.897 ml, 10 mmol) and azidotrimethylsilane (1.6 ml, 12 mmol) was added SnCl4 (40 μl) at −78° C. After addition, the cooling bath was removed and the reaction was warmed up to room temperature. After 1 hr, the reaction was worked up by partitioning between DCM (50 ml) and saturated aqueous NaHCO3 (50 ml). The aqueous layer was further extracted with DCM (20 ml). All the DCM extracts were combined, dried over MgSO4 and evaporated under reduced pressure. The residue was dissolved in 10% aqueous methanol. After 2 hr at room temperature, all the solvents were removed under reduced pressure. The title compound was obtained as a colourless oil (224 mg, 17.1%). After addition the cooling bath was removed by partitioning between DCM (50 ml) and saturated aqueous NaHCO3 (50 ml) The aqueous layer was further extracted with DCM (20 ml) dried over MgSO4 evaporated under reduced pressure The residue was dissolved in 10% aqueous methanol After 2 hr at room temperature all the solvents were removed under reduced pressure
Source ID: ord-f3ff2175a50e4443abd792b80279583aConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: To a mixture of 2-methyl dioxolane (0.897 ml, 10 mmol) and azidotrimethylsilane (1.6 ml, 12 mmol) was added SnCl4 (40 μl) at −78° C. After addition, the cooling bath was removed and the reaction was warmed up to room temperature. After 1 hr, the reaction was worked up by partitioning between DCM (50 ml) and saturated aqueous NaHCO3 (50 ml). The aqueous layer was further extracted with DCM (20 ml). All the DCM extracts were combined, dried over MgSO4 and evaporated under reduced pressure. The residue was dissolved in 10% aqueous methanol. After 2 hr at room temperature, all the solvents were removed under reduced pressure. The title compound was obtained as a colourless oil (224 mg, 17.1%). After addition the cooling bath was removed by partitioning between DCM (50 ml) and saturated aqueous NaHCO3 (50 ml) The aqueous layer was further extracted with DCM (20 ml) dried over MgSO4 evaporated under reduced pressure The residue was dissolved in 10% aqueous methanol After 2 hr at room temperature all the solvents were removed under reduced pressure
Source ID: ord-54847a8edbc94e23a43071b5f21bb99bConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: To a mixture of 2-methyl dioxolane (0.897 ml, 10 mmol) and azidotrimethylsilane (1.6 ml, 12 mmol) was added SnCl4 (40 μl) at −78° C. After addition, the cooling bath was removed and the reaction was warmed up to room temperature. After 1 hr, the reaction was worked up by partitioning between DCM (50 ml) and saturated aqueous NaHCO3 (50 ml). The aqueous layer was further extracted with DCM (20 ml). All the DCM extracts were combined, dried over MgSO4 and evaporated under reduced pressure. The residue was dissolved in 10% aqueous methanol. After 2 hr at room temperature, all the solvents were removed under reduced pressure. The title compound was obtained as a colourless oil (224 mg, 17.1%). After addition the cooling bath was removed by partitioning between DCM (50 ml) and saturated aqueous NaHCO3 (50 ml) The aqueous layer was further extracted with DCM (20 ml) dried over MgSO4 evaporated under reduced pressure The residue was dissolved in 10% aqueous methanol After 2 hr at room temperature all the solvents were removed under reduced pressure
Source ID: ord-cc48975e19b143179fa7bb118bf5ec1bConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: To a mixture of 2-methyl dioxolane (0.897 ml, 10 mmol) and azidotrimethylsilane (1.6 ml, 12 mmol) was added SnCl4 (40 μl) at −78° C. After addition, the cooling bath was removed and the reaction was warmed up to room temperature. After 1 hr, the reaction was worked up by partitioning between DCM (50 ml) and saturated aqueous NaHCO3 (50 ml). The aqueous layer was further extracted with DCM (20 ml). All the DCM extracts were combined, dried over MgSO4 and evaporated under reduced pressure. The residue was dissolved in 10% aqueous methanol. After 2 hr at room temperature, all the solvents were removed under reduced pressure. The title compound was obtained as a colourless oil (224 mg, 17.1%). After addition the cooling bath was removed by partitioning between DCM (50 ml) and saturated aqueous NaHCO3 (50 ml) The aqueous layer was further extracted with DCM (20 ml) dried over MgSO4 evaporated under reduced pressure The residue was dissolved in 10% aqueous methanol After 2 hr at room temperature all the solvents were removed under reduced pressure
Source ID: ord-a093ce7ab5824dc8ab5a5b03f983fb6dPubChem References
These sources are listed in the compound's public database record.
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