N-(phenylcarbamothioyl)benzamide

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: 12.8 g (0.05 M) of N-phenyl-N'-benzoyl-thiourea, 5.3 g (0.038M) of potassium carbonate, 4.7 ml (0.075 M) of methyliodide and 200 ml of acetone are boiled in a reflux and constantly mixed for five hours. After cooling the sediment is filtered. The filtrate is washed with 150 ml of water. The separated sediment is ground and filtered. 12.4 g (93.3% of the theoretical yield) of N-phenyl-N'-benzoyl-S-methylisothiourea with a melting point of 78°-94° are obtained. After recrystallization twice from ethanol and ethylacetate 7.4 g (54.8 % of the raw one) of product with a melting temperature of 102°-104° C. are obtained. a reflux constantly mixed for five hours After cooling the sediment is filtered The filtrate is washed with 150 ml of water filtered