(1S,2R)-cyclopropane-1,2-diamine

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: A mixture of 1-ethyl-6,7-difluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid and cis 1,2-diamino cyclopropane [Synthetic Communications, 11(6), 493-495 (1981)] in pyridine is reacted as described in Example 1 giving the desired product. is reacted

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: A mixture of 1-ethyl-6,7-difluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid and cis 1,2-diamino cyclopropane [Synthetic Communications, 11(6), 493-495 (1981)] in pyridine is reacted as described in Example 1 giving the desired product. is reacted

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: By following the processes described in stages A to C of Example R13, Example R36 is prepared by dimerization of [3-(ethoxycarbonyl)phenoxy]acetic acid with 1,2-cis-cyclopropanediamine (CAS 365996-16-3). A white powder is obtained. A white powder is obtained

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: By following the processes described in stages A to C of Example R13, Example R36 is prepared by dimerization of [3-(ethoxycarbonyl)phenoxy]acetic acid with 1,2-cis-cyclopropanediamine (CAS 365996-16-3). A white powder is obtained. A white powder is obtained

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: A mixture of 1-ethyl-6,7-difluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid and cis 1,2-diamino cyclopropane [Synthetic Communications, 11(6), 493-495 (1981)] in pyridine is reacted as described in Example 1 giving the desired product. is reacted