No renderable structure data available
C1C2=CC=CC=C2C3=CC=CC=C3C(=O)O1Chemical Intermediate
Structures, identifiers and computed properties have been matched to the database record by CAS.
| Intermediates | 7H-benzo[d][2]benzoxepin-5-one |
|---|---|
| IUPAC Name | — |
| CAS Number | 4445-34-5 |
| Database ID | 4613402 |
| Molecular Formula | — |
| Molecular Weight | — |
Product Information
7H-benzo[d][2]benzoxepin-5-one (CAS 4445-34-5) product identity, structure identifiers and related reaction data for chemical intermediate research and sourcing review.
Potential Applications
For professional research and industrial use only
Database ID 4613402
Safety Notice
For professional research and industrial use only. Review the supplier safety data sheet before handling.
Synthesis data
10 reactions · 10 references
Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-8438c58057d94efbb6110c29175cdf9dConditions: temp:170.01; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A mixture of 35 g (0.17 mol) of 7H-dibenzo[c,e]oxepin-5-one and 30.8 g (0.17 mol) of potassium phthalimide in 330 ml of DMF was heated at 170° C. for 18 h. After cooling, the deposited precipitate was filtered off with suction and introduced into 160 ml of glacial acetic acid. After stirring for 1 h, the mixture was diluted with 650 ml of ice water and the deposited product was filtered off with suction and dried in vacuo. 44.8 g of 2′-phthalimidomethylbiphenyl-2-carboxylic acid were obtained; m.p. 198° C. After cooling the deposited precipitate was filtered off with suction introduced into 160 ml of glacial acetic acid the mixture was diluted with 650 ml of ice water the deposited product was filtered off with suction dried in vacuo
Source ID: ord-60d4c94b13a949bab79c7fa14cfa1919Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: 9.0 g (0.24 mol) of sodium borohydride were added in portions at 5° C. in the course of 10 min to a suspension of 50.0 g (0.22 mol) of diphenic anhydride in 220 ml of DMF. After stirring at RT for 1 h, the reaction mixture was poured onto 220 ml of 6 M hydrochloric acid, diluted with 750 ml of water and stirred for 2 h. The deposited precipitate was filtered off with suction and 35.0 g of 7H-dibenzo[c,e]oxepin-5-one were obtained; m.p. 131° C. stirred for 2 h The deposited precipitate was filtered off with suction
Source ID: ord-1785da442b1f474b9d269908dd09b37bConditions: temp:170.01; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A mixture of 35 g (0.17 mol) of 7H-dibenzo[c,e]oxepin-5-one and 30.8 g (0.17 mol) of potassium phthalimide in 330 ml of DMF was heated at 170° C. for 18 h. After cooling, the deposited precipitate was filtered off with suction and introduced into 160 ml of glacial acetic acid. After stirring for 1 h, the mixture was diluted with 650 ml of ice water and the deposited product was filtered off with suction and dried in vacuo. 44.8 g of 2′-phthalimidomethylbiphenyl-2-carboxylic acid were obtained; m.p. 198° C. After cooling the deposited precipitate was filtered off with suction introduced into 160 ml of glacial acetic acid the mixture was diluted with 650 ml of ice water the deposited product was filtered off with suction dried in vacuo
Source ID: ord-ae240bb7a6a74f57bab520149a2665d8Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: 9.0 g (0.24 mol) of sodium borohydride were added in portions at 5° C. in the course of 10 min to a suspension of 50.0 g (0.22 mol) of diphenic anhydride in 220 ml of DMF. After stirring at RT for 1 h, the reaction mixture was poured onto 220 ml of 6 M hydrochloric acid, diluted with 750 ml of water and stirred for 2 h. The deposited precipitate was filtered off with suction and 35.0 g of 7H-dibenzo[c,e]oxepin-5-one were obtained; m.p. 131° C. stirred for 2 h The deposited precipitate was filtered off with suction
Source ID: ord-d2e8e7ec6a634f089861a868b6a4d799Conditions: temp:170.01; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A mixture of 35 g (0.17 mol) of 7H-dibenzo[c,e]oxepin-5-one and 30.8 g (0.17 mol) of potassium phthalimide in 330 ml of DMF was heated at 170° C. for 18 h. After cooling, the deposited precipitate was filtered off with suction and introduced into 160 ml of glacial acetic acid. After stirring for 1 h, the mixture was diluted with 650 ml of ice water and the deposited product was filtered off with suction and dried in vacuo. 44.8 g of 2′-phthalimidomethylbiphenyl-2-carboxylic acid were obtained; m.p. 198° C. After cooling the deposited precipitate was filtered off with suction introduced into 160 ml of glacial acetic acid the mixture was diluted with 650 ml of ice water the deposited product was filtered off with suction dried in vacuo
Source ID: ord-0b243487a8d24420b39a3ffcb3d3dd64Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: 9.0 g (0.24 mol) of sodium borohydride were added in portions at 5° C. in the course of 10 min to a suspension of 50.0 g (0.22 mol) of diphenic anhydride in 220 ml of DMF. After stirring at RT for 1 h, the reaction mixture was poured onto 220 ml of 6 M hydrochloric acid, diluted with 750 ml of water and stirred for 2 h. The deposited precipitate was filtered off with suction and 35.0 g of 7H-dibenzo[c,e]oxepin-5-one were obtained; m.p. 131° C. stirred for 2 h The deposited precipitate was filtered off with suction
Source ID: ord-9bed43b74d8d40dcb5a68ff0bb463461Conditions: temp:170.01; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A mixture of 35 g (0.17 mol) of 7H-dibenzo[c,e]oxepin-5-one and 30.8 g (0.17 mol) of potassium phthalimide in 330 ml of DMF was heated at 170° C. for 18 h. After cooling, the deposited precipitate was filtered off with suction and introduced into 160 ml of glacial acetic acid. After stirring for 1 h, the mixture was diluted with 650 ml of ice water and the deposited product was filtered off with suction and dried in vacuo. 44.8 g of 2′-phthalimidomethylbiphenyl-2-carboxylic acid were obtained; m.p. 198° C. After cooling the deposited precipitate was filtered off with suction introduced into 160 ml of glacial acetic acid the mixture was diluted with 650 ml of ice water the deposited product was filtered off with suction dried in vacuo
Source ID: ord-13d4c93e10ed4e4d8bc691f2b7318120Conditions: temp:170.01; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: A mixture of 35 g (0.17 mol) of 7H-dibenzo[c,e]oxepin-5-one and 30.8 g (0.17 mol) of potassium phthalimide in 330 ml of DMF was heated at 170° C. for 18 h. After cooling, the deposited precipitate was filtered off with suction and introduced into 160 ml of glacial acetic acid. After stirring for 1 h, the mixture was diluted with 650 ml of ice water and the deposited product was filtered off with suction and dried in vacuo. 44.8 g of 2′-phthalimidomethylbiphenyl-2-carboxylic acid were obtained; m.p. 198° C. After cooling the deposited precipitate was filtered off with suction introduced into 160 ml of glacial acetic acid the mixture was diluted with 650 ml of ice water the deposited product was filtered off with suction dried in vacuo
Source ID: ord-60d4c94b13a949bab79c7fa14cfa1919Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: 9.0 g (0.24 mol) of sodium borohydride were added in portions at 5° C. in the course of 10 min to a suspension of 50.0 g (0.22 mol) of diphenic anhydride in 220 ml of DMF. After stirring at RT for 1 h, the reaction mixture was poured onto 220 ml of 6 M hydrochloric acid, diluted with 750 ml of water and stirred for 2 h. The deposited precipitate was filtered off with suction and 35.0 g of 7H-dibenzo[c,e]oxepin-5-one were obtained; m.p. 131° C. stirred for 2 h The deposited precipitate was filtered off with suction
Source ID: ord-1785da442b1f474b9d269908dd09b37bPubChem References
These sources are listed in the compound's public database record.
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