octadecanehydrazide

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: To a solution of 20.0 g of stearic hydrazide, 21.0 g of stearic acid, 10.3 g of 1-hydroxybenzotriazole in 205.0 g of tetrahydrofuran was added 9.3 g of diisopropylcarbodiimide dropwise at room temperature, and the mixture was stirred for 3 hours under reflux. The deposited crystal was filtrated, and re-crystallized from isopropyl alcohol, to obtain 23.9 g of the intended compound. under reflux The deposited crystal was filtrated re-crystallized from isopropyl alcohol

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: To a solution of 20.0 g of stearic hydrazide, 21.0 g of stearic acid, 10.3 g of 1-hydroxybenzotriazole in 205.0 g of tetrahydrofuran was added 9.3 g of diisopropylcarbodiimide dropwise at room temperature, and the mixture was stirred for 3 hours under reflux. The deposited crystal was filtrated, and re-crystallized from isopropyl alcohol, to obtain 23.9 g of the intended compound. under reflux The deposited crystal was filtrated re-crystallized from isopropyl alcohol

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: 1.8 g (4.52 mmol) stearic acid tert-butylcarbazate is dissolved in 3 ml trifluoracetic acid, stirred for 15 min and the solvent is removed under vacuum. The mixture is treated with 30 ml dry ether and the precipitate formed is filtered out and washed twice with 50 ml dry diethyl ether. After drying under high vacuum, 1.03 g stearic acid hydrazide is obtained; Rf=0.66 (ethyl acetate/methanol 1/1) the solvent is removed under vacuum The mixture is treated with 30 ml dry ether the precipitate formed is filtered out washed twice with 50 ml dry diethyl ether After drying under high vacuum

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: To a solution of 20.0 g of stearic hydrazide, 21.0 g of stearic acid, 10.3 g of 1-hydroxybenzotriazole in 205.0 g of tetrahydrofuran was added 9.3 g of diisopropylcarbodiimide dropwise at room temperature, and the mixture was stirred for 3 hours under reflux. The deposited crystal was filtrated, and re-crystallized from isopropyl alcohol, to obtain 23.9 g of the intended compound. under reflux The deposited crystal was filtrated re-crystallized from isopropyl alcohol

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: 1.8 g (4.52 mmol) stearic acid tert-butylcarbazate is dissolved in 3 ml trifluoracetic acid, stirred for 15 min and the solvent is removed under vacuum. The mixture is treated with 30 ml dry ether and the precipitate formed is filtered out and washed twice with 50 ml dry diethyl ether. After drying under high vacuum, 1.03 g stearic acid hydrazide is obtained; Rf=0.66 (ethyl acetate/methanol 1/1) the solvent is removed under vacuum The mixture is treated with 30 ml dry ether the precipitate formed is filtered out washed twice with 50 ml dry diethyl ether After drying under high vacuum