2-iodobenzamide

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: starting from o-iodobenzamide and triethyloxonium tetrafluoroborate there is obtained ethyl o-iodobenzimidate as an oil; 1H-NMR(CDCl3): 1.42 (t, CH3), 4.38 (q, CH2), 6.8-7.6 (3 aromatic H+NH), 7.8-8.05 (1 aromatic H);

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: A total of 50 ml of a 15 M ammonium hydroxide solution was reacted with 15 g o-iodobenzoyl chloride for 20 minutes. The crude product was recovered as in Example 1. The product was recrystallized from ethanol to yield 7.8 g of o-iodobenzamide, m.p. 187°-189°, Rf 0.63. The crude product was recovered as in Example 1 The product was recrystallized from ethanol