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CCN1CC(C1)OChemical Intermediate
Structures, identifiers and computed properties have been matched to the database record by CAS.
| Intermediates | 1-ethylazetidin-3-ol |
|---|---|
| IUPAC Name | — |
| CAS Number | 35995-21-2 |
| Database ID | 13813928 |
| Molecular Formula | — |
| Molecular Weight | — |
Product Information
1-ethylazetidin-3-ol (CAS 35995-21-2) product identity, structure identifiers and related reaction data for chemical intermediate research and sourcing review.
Potential Applications
For professional research and industrial use only
Database ID 13813928
Safety Notice
For professional research and industrial use only. Review the supplier safety data sheet before handling.
Synthesis data
10 reactions · 10 references
Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-69cfbcc2493c43a79ddc78fd54e41072Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-610d1758689a455d8443d850ef065137Conditions: temp:160.01; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: To a mixture of 10.2 parts of 1-ethyl-3-azetidinol and 14.4 parts of α-naphthol 0.2 part of potassium hydroxide was added, and the mixture was heated under nitrogen gas at 160° C. for 18 hours. The reaction mixture was cooled and extracted with ether. The ether extract was washed with 2N-NaOH aqueous solution and then with water. The liquor was dried over anhydrous sodium sulfate and the solvent was distilled off. The residue was recrystallized from cyclohexane to yield 17.2 parts of 1-(α-naphthoxy)-3-ethylamino-2-propanol. The melting of the product was 106°-107° C. The yield was 70%. was added The reaction mixture was cooled extracted with ether The ether extract was washed with 2N-NaOH aqueous solution The liquor was dried over anhydrous sodium sulfate the solvent was distilled off The residue was recrystallized from cyclohexane
Source ID: ord-57e0804322d142c0a0c4f9d760ee75fdConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: The title compound is prepared from 1-ethyl-3-azetidinol and 1-fluoro-4-nitrobenzene according to the procedures of Example 5.
Source ID: ord-734b78b1e13c4ebfa6f0b8578b482c3eConditions: temp:160.01; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: To a mixture of 10.2 parts of 1-ethyl-3-azetidinol and 14.4 parts of α-naphthol 0.2 part of potassium hydroxide was added, and the mixture was heated under nitrogen gas at 160° C. for 18 hours. The reaction mixture was cooled and extracted with ether. The ether extract was washed with 2N-NaOH aqueous solution and then with water. The liquor was dried over anhydrous sodium sulfate and the solvent was distilled off. The residue was recrystallized from cyclohexane to yield 17.2 parts of 1-(α-naphthoxy)-3-ethylamino-2-propanol. The melting of the product was 106°-107° C. The yield was 70%. was added The reaction mixture was cooled extracted with ether The ether extract was washed with 2N-NaOH aqueous solution The liquor was dried over anhydrous sodium sulfate the solvent was distilled off The residue was recrystallized from cyclohexane
Source ID: ord-57e0804322d142c0a0c4f9d760ee75fdConditions: temp:160.01; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: To a mixture of 10.2 parts of 1-ethyl-3-azetidinol and 14.4 parts of α-naphthol 0.2 part of potassium hydroxide was added, and the mixture was heated under nitrogen gas at 160° C. for 18 hours. The reaction mixture was cooled and extracted with ether. The ether extract was washed with 2N-NaOH aqueous solution and then with water. The liquor was dried over anhydrous sodium sulfate and the solvent was distilled off. The residue was recrystallized from cyclohexane to yield 17.2 parts of 1-(α-naphthoxy)-3-ethylamino-2-propanol. The melting of the product was 106°-107° C. The yield was 70%. was added The reaction mixture was cooled extracted with ether The ether extract was washed with 2N-NaOH aqueous solution The liquor was dried over anhydrous sodium sulfate the solvent was distilled off The residue was recrystallized from cyclohexane
Source ID: ord-57e0804322d142c0a0c4f9d760ee75fdConditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-69cfbcc2493c43a79ddc78fd54e41072Conditions: temp:160.01; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: To a mixture of 10.2 parts of 1-ethyl-3-azetidinol and 14.4 parts of α-naphthol 0.2 part of potassium hydroxide was added, and the mixture was heated under nitrogen gas at 160° C. for 18 hours. The reaction mixture was cooled and extracted with ether. The ether extract was washed with 2 N-NaOH aqueous solution and then with water. The liquor was dried over anhydride sodium sulfate and the solvent was distilled off. The residue was recrystallized from cyclohexane to yield 17.2 parts of 1-(α-naphthoxy)-3-ethylamino-2-propanol. The melting of the product was 106°-107° C. The yield was 70%. was added The reaction mixture was cooled extracted with ether The ether extract was washed with 2 N-NaOH aqueous solution The liquor was dried over anhydride sodium sulfate the solvent was distilled off The residue was recrystallized from cyclohexane
Source ID: ord-07abf7f93f334df4a069eaad88f5ac07Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: The title compound is prepared from 1-ethyl-3-azetidinol and 1-fluoro-4-nitrobenzene according to the procedures of Example 5.
Source ID: ord-734b78b1e13c4ebfa6f0b8578b482c3eConditions: temp:160.01; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: To a mixture of 10.2 parts of 1-ethyl-3-azetidinol and 14.4 parts of α-naphthol 0.2 part of potassium hydroxide was added, and the mixture was heated under nitrogen gas at 160° C. for 18 hours. The reaction mixture was cooled and extracted with ether. The ether extract was washed with 2N-NaOH aqueous solution and then with water. The liquor was dried over anhydrous sodium sulfate and the solvent was distilled off. The residue was recrystallized from cyclohexane to yield 17.2 parts of 1-(α-naphthoxy)-3-ethylamino-2-propanol. The melting of the product was 106°-107° C. The yield was 70%. was added The reaction mixture was cooled extracted with ether The ether extract was washed with 2N-NaOH aqueous solution The liquor was dried over anhydrous sodium sulfate the solvent was distilled off The residue was recrystallized from cyclohexane
Source ID: ord-57e0804322d142c0a0c4f9d760ee75fdPubChem References
These sources are listed in the compound's public database record.
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