dimethyl 3-oxocyclopentane-1,2-dicarboxylate

Conditions: temp:0.00; pressure:0.00; stir:

Conditions: temp:0.00; pressure:0.00; stir:

Conditions: temp:0.00; pressure:0.00; stir:

Conditions: temp:0.00; pressure:0.00; stir:

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: 2,4-Bis(methoxycarbonyl)cyclopentanone (Compound 1A-A) is prepared as a mixture with 2,3-bis(methoxycarbonyl)cyclopentanone (Compound 1-Aa), e.g., by the process described in J. Org. Chem., 47, 2379 (1982). By converting the mixture into 2,4-bis(hydroxymethyl)cyclopentanone and 2,3-bis(hydroxymethyl)cyclopentanone, the two compounds can be separated from each other by silica gel column chromatography. the two compounds can be separated from each other by silica gel column chromatography