4-[(2,6-dimethylpiperidin-1-yl)methyl]aniline

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: Prepared from 1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-5,6-dimethoxy-2-indolinone and 4-[(2,6-dimethyl-piperidin-1-yl)-methyl]-aniline

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: Prepared from 1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-5,6-dimethoxy-2-indolinone and 4-[(2,6-dimethyl-piperidin-1-yl)-methyl]-aniline

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: Prepared analogously to Example 3.8. from (4′-chlorobiphenyl-4-yl)propynoic acid and 4-(2,6-dimethylpiperidin-1-ylmethyl)phenylamine. Yield: 100 mg (22% of theory); melting point: 158° C.-163° C.; C29H29ClN2O (M=457.01); calc.: molecular ion peak (M+H)+: 458/460 (Cl); found: molecular ion peak (M+H)+: 458/460 (Cl); Rf value: 0.50 (silica gel, dichloromethane/methanolic ammonia (90:10:0.1)). Prepared analogously to Example 3.8

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: Prepared from 1-acetyl-3-(1-ethoxy-1-phenylmethylene)-6-methoxycarbonyl-2-indolinone and 4-[(2,6-dimethyl-piperidin-1-yl)-methyl]-aniline Rf value: 0.5 (RP 8, methanol/five percent saline solution=4:1) C31H33N3O3

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: Prepared from 1-acetyl-3-(1-ethoxy-1-phenylmethylene)-6-ethoxycarbonyl-2-indolinone and 4-[(2,6-dimethyl-piperidin-1-yl)-methyl]-aniline Rf value: 0.6 (silica gel, methylene chloride/ethanol=5:1) C32H35N3O3

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: Prepared from 1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-5,6-dimethoxy-2-indolinone and 4-[(2,6-dimethyl-piperidin-1-yl)-methyl]-aniline

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: Prepared analogously to Example 3.8. from (4′-chlorobiphenyl-4-yl)propynoic acid and 4-(2,6-dimethylpiperidin-1-ylmethyl)phenylamine. Yield: 100 mg (22% of theory); melting point: 158° C.-163° C.; C29H29ClN2O (M=457.01); calc.: molecular ion peak (M+H)+: 458/460 (Cl); found: molecular ion peak (M+H)+: 458/460 (Cl); Rf value: 0.50 (silica gel, dichloromethane/methanolic ammonia (90:10:0.1)). Prepared analogously to Example 3.8