(E,2S,3S)-2-aminooctadec-4-ene-1,3-diol

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: The azidosphingosine was then reacted with hydrogen sulfide in pyridine (see Schmidt, Liebigs. Ann. Chem., 663-667 (1988) and U.S. Pat. No. 4,937,328, incorporated herein by reference) to yield L-threo-sphingosine. ##STR10##

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: The azidosphingosine was then reacted with hydrogen sulfide in pyridine (see Schmidt, Liebigs. Ann. Chem., 663-667 (1988) and U.S. Pat. No. 4,937,328, incorporated herein by reference) to yield L-threo-sphingosine. ##STR10##

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: The azidosphingosine was then reacted with hydrogen sulfide in pyridine (see Schmidt, Liebigs. Ann. Chem., 663-667 (1988) and U.S. Pat. No. 4,937,328, incorporated herein by reference) to yield L-threo-sphingosine. ##STR10##

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: The azidosphingosine was then reacted with hydrogen sulfide in pyridine (see Schmidt, Liebigs. Ann. Chem., 663-667 (1988) and U.S. Pat. No. 4,937,328, incorporated herein by reference) to yield L-threo-sphingosine. ##STR10##

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: The azidosphingosine was then reacted with hydrogen sulfide in pyridine (see Schmidt, Liebigs. Ann. Chem., 663-667 (1988) and U.S. Pat. No. 4,937,328, incorporated herein by reference) to yield L-threo-sphingosine. ##STR10##

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: The azidosphingosine was then reacted with hydrogen sulfide in pyridine (see Schmidt, Liebigs. Ann. Chem., 663-667 (1988) and U.S. Pat. No. 4,937,328, incorporated herein by reference) to yield L-threo-sphingosine. ##STR10##