N-methyloctadecan-1-amine

Conditions: temp:0.00; pressure:0.00; stir:

Conditions: temp:0.00; pressure:0.00; stir:

Conditions: temp:0.00; pressure:0.00; stir:

Conditions: temp:0.00; pressure:0.00; stir:

Conditions: temp:0.00; pressure:0.00; stir:

Conditions: temp:0.00; pressure:0.00; stir:

Conditions: temp:100.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: A mixture of 5.7 g ethyl-3-diphenylphosphinopropionate (9.9 mmoles), 5.1 g N-methyl-n-octadecylamine (18.0 mmoles), and 0.3 g sodium methoxide (5.6 mmoles) were first deoxygenated and then heated to 100° C. under a nitrogen atmosphere for 24 hours. The mixture was then cooled and extracted with pentane. The pentane soluble was rotovapped to an oil. were first deoxygenated The mixture was then cooled extracted with pentane

Conditions: temp:0.00; pressure:0.00; stir:

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: [2-(2-Hydroxyethyl)piperidine is reacted with phenyl chlorocarbonate in methylene chloride in the presence of pyridine and further reacted with N-methyl-N-octadecylamine to obtain [2-(2-hydroxyethyl)piperidino]-N-methyl-N-octadecyl formamide.

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: 44 g of 5-nitro-2-chlorobenzenesulfonylchloride and 100 ml of dichloromethane were mixed. A dichloromethane solution of 48.4 g of methyloctadecylamine and 36.1 ml of triethylamine was added dropwise to the mixture. After the reaction was completed, the reaction solvent was removed under reduced pressure. 300 ml of methanol was added to the reaction system so that dissolution was effected. The solution was then gradually allowed to cool. As a result, crystals precipitated. The crystals were filtered, and then dried. the reaction solvent was removed under reduced pressure 300 ml of methanol was added to the reaction system so that dissolution to cool As a result, crystals precipitated The crystals were filtered dried

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: 44 g of 5-nitro-2-chlorobenzenesulfonylchloride and 100 ml of dichloromethane were mixed. A dichloromethane solution of 48.4 g of methyloctadecylamine and 36.1 ml of triethylamine was added dropwise to the mixture. After the reaction was completed, the reaction solvent was removed under reduced pressure. 300 ml of methanol was added to the reaction system so that dissolution was effected. The solution was then gradually allowed to cool. As a result, crystals precipitated. The crystals were filtered, and then dried. the reaction solvent was removed under reduced pressure 300 ml of methanol was added to the reaction system so that dissolution to cool As a result, crystals precipitated The crystals were filtered dried

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: N-n-dodecyl-(5-tert.-butyl-2,3-dimethyl-4-hydroxyphenyl)acetamide is made by an analogous procedure by substituting n-dodecylamine for N-methyl-N-n-octadecylamine.