pyrrolidine-2-thione

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: A 50 ml. glacial acetic acid solution of 3.0 g. (0.03 m.) 2-pyrrolidinethione and 6.5 g. (0.03 m.) α-bromophenylacetic acid is heated on a steam bath for 5 hours. The solution is cooled and the precipitated solid is collected and washed with acetone and ether. The 7.0 g. of solid is recrystallized from acetonitrile to give 4.2 g. (47% yield) of title compound, m.p. 200°-205° C. The solution is cooled the precipitated solid is collected washed with acetone and ether of solid is recrystallized from acetonitrile to give 4.2 g