No renderable structure data available
COC(=O)CCCCC1=CC=CC=C1Chemical Intermediate
Structures, identifiers and computed properties have been matched to the database record by CAS.
| Intermediates | methyl 5-phenylpentanoate |
|---|---|
| IUPAC Name | — |
| CAS Number | 20620-59-1 |
| Database ID | 262942 |
| Molecular Formula | — |
| Molecular Weight | — |
Product Information
methyl 5-phenylpentanoate (CAS 20620-59-1) product identity, structure identifiers and related reaction data for chemical intermediate research and sourcing review.
Potential Applications
For professional research and industrial use only
Database ID 262942
Safety Notice
For professional research and industrial use only. Review the supplier safety data sheet before handling.
Synthesis data
12 reactions · 12 references
Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-3e2fdcf7e127499bb8aac649d7688485Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: To a solution of 5.12 g of methyl 5-phenylvalerate in 25 ml of carbon disulfide, 7.10 g of anhydrous aluminium chloride was added under ice-cooling, and then 4.11 g of phenylacetyl chloride was added dropwise and stirring was continued at room temperature for 6 hours. The reaction mixture was poured into ice-water and extracted with methylene chloride. The methylene chloride layer was washed successively with water, aqueous potassium carbonate solution and water, dried, and then the solvent was removed under reduced pressure. The residue was purified by column chromatography on silica gel (methylene chloride:n-hexane=2:1) to afford 5.45 g of colorless crystals. Recrystallization from isopropyl ether gave colorless flakes, mp 53.5°~54° C. cooling extracted with methylene chloride The methylene chloride layer was washed successively with water, aqueous potassium carbonate solution and water dried the solvent was removed under reduced pressure The residue was purified by column chromatography on silica gel (methylene chloride:n-hexane=2:1)
Source ID: ord-cf89ed08037e4da49af3bb39c23e54caConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: 5-Phenylpentanoic acid (10.0 g) was dissolved in 250 mL of methanol and sparged with hydrogen chloride gas at room temperature for 15 minutes. The solvent was then removed under vacuum. Methyl 5-phenylpentanoate obtained was used in the next step without further purification. sparged with hydrogen chloride gas at room temperature for 15 minutes The solvent was then removed under vacuum
Source ID: ord-52b9d2f7e6f34c908162e0c1dcef44eaConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: 5-Phenylpentanoic acid (10.0 g) was dissolved in 250 mL of methanol and sparged with hydrogen chloride gas at room temperature for 15 minutes. The solvent was then removed under vacuum. Methyl 5-phenylpentanoate obtained was used in the next step without further purification. sparged with hydrogen chloride gas at room temperature for 15 minutes The solvent was then removed under vacuum
Source ID: ord-52b9d2f7e6f34c908162e0c1dcef44eaConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: 5-Phenylpentanoic acid (10.0 g) was dissolved in 250 mL of methanol and sparged with hydrogen chloride gas at room temperature for 15 minutes. The solvent was then removed under vacuum. Methyl 5-phenylpentanoate obtained was used in the next step without further purification. sparged with hydrogen chloride gas at room temperature for 15 minutes The solvent was then removed under vacuum
Source ID: ord-2a81acb623ca4142a41d1a84e27f9511Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: 5-Phenylpentanoic acid (10.0 g) was dissolved in 250 mL of methanol and sparged with hydrogen chloride gas at room temperature for 15 minutes. The solvent was then removed under vacuum. Methyl 5-phenylpentanoate obtained was used in the next step without further purification. sparged with hydrogen chloride gas at room temperature for 15 minutes The solvent was then removed under vacuum
Source ID: ord-0a54314509774b6d87c74f678b21d28aConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: 5-Phenylpentanoic acid (10.0 g) was dissolved in 250 mL of methanol and sparged with hydrogen chloride gas at room temperature for 15 minutes. The solvent was then removed under vacuum. Methyl 5-phenylpentanoate obtained was used in the next step without further purification. sparged with hydrogen chloride gas at room temperature for 15 minutes The solvent was then removed under vacuum
Source ID: ord-0a54314509774b6d87c74f678b21d28aConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: To a solution of 5.12 g of methyl 5-phenylvalerate in 25 ml of carbon disulfide, 7.10 g of anhydrous aluminium chloride was added under ice-cooling, and then 4.11 g of phenylacetyl chloride was added dropwise and stirring was continued at room temperature for 6 hours. The reaction mixture was poured into ice-water and extracted with methylene chloride. The methylene chloride layer was washed successively with water, aqueous potassium carbonate solution and water, dried, and then the solvent was removed under reduced pressure. The residue was purified by column chromatography on silica gel (methylene chloride:n-hexane=2:1) to afford 5.45 g of colorless crystals. Recrystallization from isopropyl ether gave colorless flakes, mp 53.5°~54° C. cooling extracted with methylene chloride The methylene chloride layer was washed successively with water, aqueous potassium carbonate solution and water dried the solvent was removed under reduced pressure The residue was purified by column chromatography on silica gel (methylene chloride:n-hexane=2:1)
Source ID: ord-cf89ed08037e4da49af3bb39c23e54caConditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-3e2fdcf7e127499bb8aac649d7688485Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: 5-Phenylpentanoic acid (10.0 g) was dissolved in 250 mL of methanol and sparged with hydrogen chloride gas at room temperature for 15 minutes. The solvent was then removed under vacuum. Methyl 5-phenylpentanoate obtained was used in the next step without further purification. sparged with hydrogen chloride gas at room temperature for 15 minutes The solvent was then removed under vacuum
Source ID: ord-b6e0bed03fc2493d95c2917ba598e818Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: 5-Phenylpentanoic acid (10.0 g) was dissolved in 250 mL of methanol and sparged with hydrogen chloride gas at room temperature for 15 minutes. The solvent was then removed under vacuum. Methyl 5-phenylpentanoate obtained was used in the next step without further purification. sparged with hydrogen chloride gas at room temperature for 15 minutes The solvent was then removed under vacuum
Source ID: ord-b6e0bed03fc2493d95c2917ba598e818Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: 5-Phenylpentanoic acid (10.0 g) was dissolved in 250 mL of methanol and sparged with hydrogen chloride gas at room temperature for 15 minutes. The solvent was then removed under vacuum. Methyl 5-phenylpentanoate obtained was used in the next step without further purification. sparged with hydrogen chloride gas at room temperature for 15 minutes The solvent was then removed under vacuum
Source ID: ord-b6e0bed03fc2493d95c2917ba598e818PubChem References
These sources are listed in the compound's public database record.
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