2-oxopent-4-enoic acid

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: In the manner given in Example 9, 7-chloro-2-hydrazino-5-(o-chlorophenyl)-3H-1,4-benzodiazepine can be stirred with 2-oxo-4-pentenoic acid at room temperature to give 7-chloro-2-[(1-carboxy-3-butenylidene)-hydrazino]-5-(o-chlorophenyl)-3H-1,4-benzodiazepine.

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: In the manner given in Example 9, 7-chloro-2-hydrazino-5-(o-chlorophenyl)-3H-1,4-benzodiazepine can be stirred with 2-oxo-4-pentenoic acid at room temperature to give 7-chloro-2-[(1-carboxy-3-butenylidene)-hydrazino]-5-(o-chlorophenyl)-3H-1,4-benzodiazepine.

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: In the manner given in Example 9, 7-chloro-2-hydrazino-5-(o-chlorophenyl)-3H-1,4-benzodiazepine can be stirred with 2-oxo-4-pentenoic acid at room temperature to give 7-chloro-2-[(1-carboxy-3-butenylidene)-hydrazino]-5-(o-chlorophenyl)-3H-1,4-benzodiazepine.

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: In the manner given in Example 9, 7-chloro-2-hydrazino-5-(o-chlorophenyl)-3H-1,4-benzodiazepine can be stirred with 2-oxo-4-pentenoic acid at room temperature to give 7-chloro-2-[(1-carboxy-3-butenylidene)-hydrazino]-5-(o-chlorophenyl)-3H-1,4-benzodiazepine.