No renderable structure data available
C1CCN(C1)C(=O)C2CCCN2Chemical Intermediate
Structures, identifiers and computed properties have been matched to the database record by CAS.
| Intermediates | pyrrolidin-1-yl(pyrrolidin-2-yl)methanone |
|---|---|
| IUPAC Name | — |
| CAS Number | 202990-49-6 |
| Database ID | 550904 |
| Molecular Formula | — |
| Molecular Weight | — |
Product Information
pyrrolidin-1-yl(pyrrolidin-2-yl)methanone (CAS 202990-49-6) product identity, structure identifiers and related reaction data for chemical intermediate research and sourcing review.
Potential Applications
For professional research and industrial use only
Database ID 550904
Safety Notice
For professional research and industrial use only. Review the supplier safety data sheet before handling.
Synthesis data
12 reactions · 12 references
Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-662c520da7334cfdbc5ba814399bdb6cConditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-86894d54dfae466cb88d2d43bebab099Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-e600323959a64b11ab50cdf260c6050cConditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-67eeb917eef24ca8bc163e84ede2e865Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: Lithium aluminum hydride (9 g) is suspended in dry tetrahydrofuran (100 ml) under ice-cooling, and thereto is added dropwise a solution of 2-(1-pyrrolidinyl)carbonylpyrrolidine (33 g) in dry tetrahydrofuran (80 ml). The mixture is refluxed under nitrogen atmosphere for four hours. The mixture is cooled with ice, and thereto is added a saturated aqueous sodium sulfate solution (about 15 ml), and then mixture is further stirred at room temperature for three hours. The precipitated sodium sulfate is removed by filtration, washed well with chloroform. The filtrate and the washings are combined, concentrated under reduced pressure, and evaporated to give 2-(1-pyrrolidinyl)methylpyrrolidine (22 g). cooling The mixture is refluxed under nitrogen atmosphere for four hours The mixture is cooled with ice The precipitated sodium sulfate is removed by filtration washed well with chloroform concentrated under reduced pressure evaporated
Source ID: ord-c1131094427749b29a96b4a0c315abbbConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: In ethanol (300 ml) is suspended 5% palladium-carbon (3 g), and thereto is added 2-(1-pyrrolidinyl)carbonyl-1-benzylpyrrolidine (30 g), and the mixture is subjected to catalytic hydrogenation at room temperature under atmospheric pressure. The mixture is filtered, and the filtrate is concentrated under reduced pressure to remove the solvent to give 2-(1-pyrrolidinyl)carbonylpyrrolidine (about 18 g) as an oily product. is subjected to catalytic hydrogenation at room temperature under atmospheric pressure The mixture is filtered the filtrate is concentrated under reduced pressure to remove the solvent
Source ID: ord-3fc5a98fccb24020a84daa4a512926d3Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-662c520da7334cfdbc5ba814399bdb6cConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: Lithium aluminum hydride (9 g) is suspended in dry tetrahydrofuran (100 ml) under ice-cooling, and thereto is added dropwise a solution of 2-(1-pyrrolidinyl)carbonylpyrrolidine (33 g) in dry tetrahydrofuran (80 ml). The mixture is refluxed under nitrogen atmosphere for four hours. The mixture is cooled with ice, and thereto is added a saturated aqueous sodium sulfate solution (about 15 ml), and then mixture is further stirred at room temperature for three hours. The precipitated sodium sulfate is removed by filtration, washed well with chloroform. The filtrate and the washings are combined, concentrated under reduced pressure, and evaporated to give 2-(1-pyrrolidinyl)methylpyrrolidine (22 g). cooling The mixture is refluxed under nitrogen atmosphere for four hours The mixture is cooled with ice The precipitated sodium sulfate is removed by filtration washed well with chloroform concentrated under reduced pressure evaporated
Source ID: ord-c1131094427749b29a96b4a0c315abbbConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: Lithium aluminum hydride (9 g) is suspended in dry tetrahydrofuran (100 ml) under ice-cooling, and thereto is added dropwise a solution of 2-(1-pyrrolidinyl)carbonylpyrrolidine (33 g) in dry tetrahydrofuran (80 ml). The mixture is refluxed under nitrogen atmosphere for four hours. The mixture is cooled with ice, and thereto is added a saturated aqueous sodium sulfate solution (about 15 ml), and then mixture is further stirred at room temperature for three hours. The precipitated sodium sulfate is removed by filtration, washed well with chloroform. The filtrate and the washings are combined, concentrated under reduced pressure, and evaporated to give 2-(1-pyrrolidinyl)methylpyrrolidine (22 g). cooling The mixture is refluxed under nitrogen atmosphere for four hours The mixture is cooled with ice The precipitated sodium sulfate is removed by filtration washed well with chloroform concentrated under reduced pressure evaporated
Source ID: ord-c1131094427749b29a96b4a0c315abbbConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: In ethanol (300 ml) is suspended 5% palladium-carbon (3 g), and thereto is added 2-(1-pyrrolidinyl)carbonyl-1-benzylpyrrolidine (30 g), and the mixture is subjected to catalytic hydrogenation at room temperature under atmospheric pressure. The mixture is filtered, and the filtrate is concentrated under reduced pressure to remove the solvent to give 2-(1-pyrrolidinyl)carbonylpyrrolidine (about 18 g) as an oily product. is subjected to catalytic hydrogenation at room temperature under atmospheric pressure The mixture is filtered the filtrate is concentrated under reduced pressure to remove the solvent
Source ID: ord-3fc5a98fccb24020a84daa4a512926d3Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-86894d54dfae466cb88d2d43bebab099Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-e600323959a64b11ab50cdf260c6050cPubChem References
These sources are listed in the compound's public database record.
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