No renderable structure data available
CS(=O)(=O)C1=C(C=C(C=C1)CO)FChemical Intermediate
Structures, identifiers and computed properties have been matched to the database record by CAS.
| Intermediates | (3-fluoro-4-methylsulfonylphenyl)methanol |
|---|---|
| IUPAC Name | — |
| CAS Number | 1564471-90-4 |
| Database ID | 67219085 |
| Molecular Formula | — |
| Molecular Weight | — |
Product Information
(3-fluoro-4-methylsulfonylphenyl)methanol (CAS 1564471-90-4) product identity, structure identifiers and related reaction data for chemical intermediate research and sourcing review.
Potential Applications
For professional research and industrial use only
Database ID 67219085
Safety Notice
For professional research and industrial use only. Review the supplier safety data sheet before handling.
Synthesis data
12 reactions · 12 references
Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-89cd89e4998d4356a81addbb1b86c130Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-914f78e4044d4b979b9bf7d822c270e2Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-89cd89e4998d4356a81addbb1b86c130Conditions: temp:0.00; pressure:0.00; stir:
Source ID: ord-914f78e4044d4b979b9bf7d822c270e2Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: To a stirred suspension of (3-fluoro-4-methanesulfonyl-phenyl)-methanol (0.269 g, 1.31 mmol) in diethyl ether (5 ml) under an inert atmosphere of Argon is added dropwise phosphorus tribromide (46 μl, 0.434 mmol). After stirring at room temperature overnight, the reaction mixture is diluted with water (2 ml) and the diethyl ether layer separated. This organic portion is placed over NaOH pellets and after 20 minutes, is used as a reagent in solution in diethyl ether. the diethyl ether layer separated This organic portion is placed over NaOH pellets and after 20 minutes
Source ID: ord-11b1a8b9552c4759a9a6baf5de387613Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: To an ice-cooled suspension of 3-fluoro-4-methanesulfonyl-benzaldehyde (1.3 g, 6.44 mmol) in ethanol (5 ml) under an inert atmosphere of Argon is added sodium borohydride (0.275 g, 7.27 mmol) portionwise over 2-3 minutes. After stirring for 4 hours, the reaction mixture is poured carefully onto ice-cold water and acidified to pH 1 using 1M HCl. The product is extracted into ethyl acetate (80 ml) and this organic portion is washed with brine, dried over MgSO4 and the solvent is removed in vacuo to give an oil which solidifies on drying to yield the titled compound. the reaction mixture is poured carefully onto ice-cold water The product is extracted into ethyl acetate (80 ml) this organic portion is washed with brine dried over MgSO4 the solvent is removed in vacuo to give an oil which on drying
Source ID: ord-eb02f3ebf4164427b4a69ead2b2fd9ceConditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: To a stirred suspension of (3-fluoro-4-methanesulfonyl-phenyl)-methanol (0.269 g, 1.31 mmol) in diethyl ether (5 ml) under an inert atmosphere of Argon is added dropwise phosphorus tribromide (46 μl, 0.434 mmol). After stirring at room temperature overnight, the reaction mixture is diluted with water (2 ml) and the diethyl ether layer separated. This organic portion is placed over NaOH pellets and after 20 minutes, is used as a reagent in solution in diethyl ether. the diethyl ether layer separated This organic portion is placed over NaOH pellets and after 20 minutes
Source ID: ord-a6a34979c60d41039434a9ebfc9bc964Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: To an ice-cooled suspension of 3-fluoro-4-methanesulfonyl-benzaldehyde (1.3 g, 6.44 mmol) in ethanol (5 ml) under an inert atmosphere of Argon is added sodium borohydride (0.275 g, 7.27 mmol) portionwise over 2-3 minutes. After stirring for 4 hours, the reaction mixture is poured carefully onto ice-cold water and acidified to pH 1 using 1M HCl. The product is extracted into ethyl acetate (80 ml) and this organic portion is washed with brine, dried over MgSO4 and the solvent is removed in vacuo to give an oil which solidifies on drying to yield the titled compound. the reaction mixture is poured carefully onto ice-cold water The product is extracted into ethyl acetate (80 ml) this organic portion is washed with brine dried over MgSO4 the solvent is removed in vacuo to give an oil which on drying
Source ID: ord-e96a3042bda4449db98c3f2925e69fa6Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: To a stirred suspension of (3-fluoro-4-methanesulfonyl-phenyl)-methanol (0.269 g, 1.31 mmol) in diethyl ether (5 ml) under an inert atmosphere of Argon is added dropwise phosphorus tribromide (46 μl, 0.434 mmol). After stirring at room temperature overnight, the reaction mixture is diluted with water (2 ml) and the diethyl ether layer separated. This organic portion is placed over NaOH pellets and after 20 minutes, is used as a reagent in solution in diethyl ether. the diethyl ether layer separated This organic portion is placed over NaOH pellets and after 20 minutes
Source ID: ord-6da6ffa57eeb45bf82ad222c5a9ebe77Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: To an ice-cooled suspension of 3-fluoro-4-methanesulfonyl-benzaldehyde (1.3 g, 6.44 mmol) in ethanol (5 ml) under an inert atmosphere of Argon is added sodium borohydride (0.275 g, 7.27 mmol) portionwise over 2-3 minutes. After stirring for 4 hours, the reaction mixture is poured carefully onto ice-cold water and acidified to pH 1 using 1M HCl. The product is extracted into ethyl acetate (80 ml) and this organic portion is washed with brine, dried over MgSO4 and the solvent is removed in vacuo to give an oil which solidifies on drying to yield the titled compound. the reaction mixture is poured carefully onto ice-cold water The product is extracted into ethyl acetate (80 ml) this organic portion is washed with brine dried over MgSO4 the solvent is removed in vacuo to give an oil which on drying
Source ID: ord-32b7efe2650848c38ac55c3d6aabaa93Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: To a stirred suspension of (3-fluoro-4-methanesulfonyl-phenyl)-methanol (0.269 g, 1.31 mmol) in diethyl ether (5 ml) under an inert atmosphere of Argon is added dropwise phosphorus tribromide (46 μl, 0.434 mmol). After stirring at room temperature overnight, the reaction mixture is diluted with water (2 ml) and the diethyl ether layer separated. This organic portion is placed over NaOH pellets and after 20 minutes, is used as a reagent in solution in diethyl ether. the diethyl ether layer separated This organic portion is placed over NaOH pellets and after 20 minutes
Source ID: ord-742e340260444d9f9f465ef3beff4e89Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.
Procedure: To an ice-cooled suspension of 3-fluoro-4-methanesulfonyl-benzaldehyde (1.3 g, 6.44 mmol) in ethanol (5 ml) under an inert atmosphere of Argon is added sodium borohydride (0.275 g, 7.27 mmol) portionwise over 2-3 minutes. After stirring for 4 hours, the reaction mixture is poured carefully onto ice-cold water and acidified to pH 1 using 1M HCl. The product is extracted into ethyl acetate (80 ml) and this organic portion is washed with brine, dried over MgSO4 and the solvent is removed in vacuo to give an oil which solidifies on drying to yield the titled compound. the reaction mixture is poured carefully onto ice-cold water The product is extracted into ethyl acetate (80 ml) this organic portion is washed with brine dried over MgSO4 the solvent is removed in vacuo to give an oil which on drying
Source ID: ord-ba3b1e92f2a84578939e72dbfe91ed03PubChem References
These sources are listed in the compound's public database record.
Request a Quote
Send the required specification, quantity, destination and intended use. The CATO team will review availability and respond.