1-(4-bromo-2-hydroxyphenyl)-2-methylpropan-1-one

Conditions: temp:80.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: 40.8 g (1.08 mol) of sodium borohydride are added to 1,100 ml of isopropanol, and 261 g (1.08 mol) of the 5-bromo-2-(1-methylethylcarbonyl)phenol from Example 2, dissolved in 300 ml of isopropanol, are added dropwise. The mixture is subsequently stirred at 80° C. for 2 hours and cooled, the solvent is removed, and the residue obtained is taken up in methyl tert-butyl ether (MTBE) and ice water. The mixture is extracted by shaking, the organic phase is separated off, and the aqueous phase is back-extracted several times with MTBE. The combined organic phases are dried and freed from solvent at 20° C. under reduced pressure. The residue obtained in this way is recrystallized from n-hexane, an optimum yield being obtained by cooling the mixture to -40° C. for crystallization. are added dropwise cooled the solvent is removed the residue obtained The mixture is extracted by shaking the organic phase is separated off the aqueous phase is back-extracted several times with MTBE The combined organic phases are dried freed from solvent at 20° C. under reduced pressure The residue obtained in this way is recrystallized from n-hexane an optimum yield being obtained by cooling the mixture to -40° C. for crystallization

Conditions: temp:80.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: 40.8 g (1.08 mol) of sodium borohydride are added to 1,100 ml of isopropanol, and 261 g (1.08 mol) of the 5-bromo-2-(1-methylethylcarbonyl)phenol from Example 2, dissolved in 300 ml of isopropanol, are added dropwise. The mixture is subsequently stirred at 80° C. for 2 hours and cooled, the solvent is removed, and the residue obtained is taken up in methyl tert-butyl ether (MTBE) and ice water. The mixture is extracted by shaking, the organic phase is separated off, and the aqueous phase is back-extracted several times with MTBE. The combined organic phases are dried and freed from solvent at 20° C. under reduced pressure. The residue obtained in this way is recrystallized from n-hexane, an optimum yield being obtained by cooling the mixture to -40° C. for crystallization. are added dropwise cooled the solvent is removed the residue obtained The mixture is extracted by shaking the organic phase is separated off the aqueous phase is back-extracted several times with MTBE The combined organic phases are dried freed from solvent at 20° C. under reduced pressure The residue obtained in this way is recrystallized from n-hexane an optimum yield being obtained by cooling the mixture to -40° C. for crystallization

Conditions: temp:80.01; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: 40.8 g (1.08 mol) of sodium borohydride are added to 1,100 ml of isopropanol, and 261 g (1.08 mol) of the 5-bromo-2-(1-methylethylcarbonyl)phenol from Example 2, dissolved in 300 ml of isopropanol, are added dropwise. The mixture is subsequently stirred at 80° C. for 2 hours and cooled, the solvent is removed, and the residue obtained is taken up in methyl tert-butyl ether (MTBE) and ice water. The mixture is extracted by shaking, the organic phase is separated off, and the aqueous phase is back-extracted several times with MTBE. The combined organic phases are dried and freed from solvent at 20° C. under reduced pressure. The residue obtained in this way is recrystallized from n-hexane, an optimum yield being obtained by cooling the mixture to -40° C. for crystallization. are added dropwise cooled the solvent is removed the residue obtained The mixture is extracted by shaking the organic phase is separated off the aqueous phase is back-extracted several times with MTBE The combined organic phases are dried freed from solvent at 20° C. under reduced pressure The residue obtained in this way is recrystallized from n-hexane an optimum yield being obtained by cooling the mixture to -40° C. for crystallization