(3-tert-butylphenyl)methanamine

Conditions: temp:0.00; pressure:0.00; stir:

Conditions: temp:0.00; pressure:0.00; stir:

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: To 3-tert-butylbenzonitrile (400 mg) in MeOH (5 mL), aqueous ammonium hydroxide (1 mL) and Raney Nickel (catalytic) were added and the reaction mixture was hydrogenated at 50 psi for 2 h. Then the reaction mixture was filtered and solvent evaporated. (3-tert-butylphenyl)methanamine was used without any purification. Then the reaction mixture was filtered solvent evaporated (3-tert-butylphenyl)methanamine was used without any purification

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: The following compounds can be obtained by a similar procedure, using 3-cyclopropyl-benzylamine, C-(5-bromo-pyridine-3-yl)methylamine, C-(5-cyclopropyl-pyridine-3-yl)-methylamine, C-(2-cyclopropyl-pyridine-4-yl)-methylamine, 6 isopropyl-2,2-dimethyl-chroman-4(R/S)-ylamine, 3-tert-butyl-benzylamine or 3-(2,2-dimethyl-propyl)-benzylamine instead of 3-isopropyl-benzylamine: The following compounds can be obtained by a similar procedure