methyl N-(2-hydroxyethyl)carbamate

Conditions: temp:0.00; pressure:0.00; stir:

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: by using methyl 2-hydroxyethylcarbamate and bromoacetyl bromide there is obtained methyl 2-bromoacetoxyethylcarbamate, nD20 1.4891;

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: by using methyl 2-hydroxyethylcarbamate and 2-bromopropionyl bromide there is obtained methyl 2-(2-bromopropionyloxy)-ethylcarbamate, nD20 1.4779;

Conditions: temp:0.00; pressure:0.00; stir:

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: by using methyl 2-hydroxyethylcarbamate and bromoacetyl bromide there is obtained methyl 2-bromoacetoxyethylcarbamate, nD20 1.4891;

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: by using methyl 2-hydroxyethylcarbamate and bromoacetyl bromide there is obtained methyl 2-bromoacetoxyethylcarbamate, nD20 1.4891;

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: by using methyl 2-hydroxyethylcarbamate and 2-bromopropionyl bromide there is obtained methyl 2-(2-bromopropionyloxy)-ethylcarbamate, nD20 1.4779;

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: starting from 5,7-dihydro-6H-dibenz[c,e]azepine-6-carbonitrile and methyl 2-hydroxyethylcarbamate, there is obtained 2-methoxycarbonylamino-ethyl 5,7-dihydro-6H-dibenz[c,e]azepine-6-carboximidate as a resin, mass spectrum m/e: M+ 339 (5), 308 (2), 237 (22), 194 (56), 102 (100);

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: 9.0 g of methyl 2-hydroxyethylcarbamate and 6.7 g of pyridine are dissolved in 70 ml of diethyl ether and cooled to 0°-5° C. 18.0 g of 2-bromopropionyl bromide, dissolved in 20 ml of diethyl ether are now added dropwise within 30 minutes and the mixture is stirred at ice temperature for a further 30 minutes and at room temperature for 1 hour. For the working-up, the mixture is poured into water and extracted with diethyl ether. The ether phase is washed twice with sodium chloride solution, dried over anhydrous sodium sulphate and evaporated under reduced pressure. There is obtained methyl 2-(2-bromopropionyloxy)ethylcarbamate as a yellow oil which is used without further purification. cooled to 0°-5° C are now added dropwise within 30 minutes extracted with diethyl ether The ether phase is washed twice with sodium chloride solution dried over anhydrous sodium sulphate evaporated under reduced pressure

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: by using methyl 2-hydroxyethylcarbamate and bromoacetyl bromide there is obtained methyl 2-bromoacetoxyethylcarbamate, nD20 1.4891;

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: by using methyl 2-hydroxyethylcarbamate and 2-bromopropionyl bromide there is obtained methyl 2-(2-bromopropionyloxy)-ethylcarbamate, nD20 1.4779;