2-(2-methoxyethylamino)-2-methylpropan-1-ol

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: In analogy to the procedure described in Example 47 b), 6-cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (Example 1 b)) was reacted with 2-(2-methoxyethylamino)-2-methylpropan-1-ol (CAN 1156380-97-0) in the presence of TBTU and DIEA to obtain the title compound as colorless oil; MS (EI): m/e=414.4 [MH+].

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: In analogy to the procedure described in Example 47 b), 6-cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (Example 1 b)) was reacted with 2-(2-methoxyethylamino)-2-methylpropan-1-ol (CAN 1156380-97-0) in the presence of TBTU and DIEA to obtain the title compound as colorless oil; MS (EI): m/e=414.4 [MH+].