3-[2-(4-methylpiperazin-1-yl)ethyl]aniline

Conditions: temp:0.00; pressure:0.00; stir:; See reaction.notes.procedure_details.

Procedure: Following general procedure C, (6-bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone (240 mg, 0.77 mmol) was reacted with 3-(2-(4-methylpiperazin-1-yl)ethyl)aniline (170 mg, 0.77 mmol) to afford the desired product (212 mg, 55%) as a yellow solid: ESI MS m/z 493 [C26H29BrN4O+H]+.